| Content | CJC-1295 is a synthetic GHRH (growth hormone releasing hormone) analogue made up of 30 amino acids. It has been found to be highly effective with regards to the increase of growth hormone secretion and IGF-1 without negatively affecting the pulsatility of GH secretion.
CJC-1295 is often combined with Ipamorelin due to its enhanced specificity as a GHRH. This peptide generates similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other peptides in its class. This peptide has been found to be very well-tolerated and perfect when combined with Ipamorelin.
Gland Stimulated: Pituitary
Benefits of CJC-1295:
Increased growth hormone secretion and IGF-1 Levels with no increase in prolactin
Increased Body Weight and Length through increased protein synthesis
Increased Muscle Growth
Increased Bone Density
Improved Immune Function
Improved Cognition and Memory
Increased Collagen Production
Increased Fat Loss
Increased Cellular Repair and Regeneration
CJC-1295 also promotes slow wave deep sleep, which is responsible for the highest level of muscle growth and memory retention and rejuvenation
Two types of CJC 1295:
GHRH (growth hormone releasing hormone) is produced in the hypothalamus. Its pulsatile release from the hypothalamus triggers a pulsatile release of GH from the pituitary gland. GHRH has a very short half-life of only a few minutes (half-life = the time required to remove half of the substance from the blood. The shorter the half-life, the more rapidly the substance is removed from the body, and the less its effect on the body).
The first 29 amino acids of GHRH is the active segment. They are available as a manufactured peptide called Sermorelin. Sermorelin was further modified to increase its half-life to 30 minutes. This is called CJC 1295. CJC-1295 was further modified by adding DAC (Drug Affinity Complex) to it. DAC binds to a blood protein called albumin, which increases it's half-life to 8 days. It is called CJC 1295 + DAC. CJC 1295 can also be compounded in a non-DAC form which mimics a more normal physiologic GH spike each night.
The longer half-life from the DAC binding to albumin means injections are only required once or twice per week. However, the long half-life and relatively constant blood level provide a constant stimulus for GH release from the pituitary through the GHRH receptor, which is not physiological. This can decrease the GH pulse amplitude which will result in decreased GH tissue stimulation.
Safety:
It is recommended when using a long-acting CJC molecule to have 'hormone holidays' of three months each three to six months, to allow the pituitary to 'recover'. During the holidays, Sermorelin is used instead of CJC 1295 + DAC.
The 'hormone holidays' may also minimize the risk of GH resistance developing. This resistance, or insensitivity, may occur via antibodies forming that bind to and inactivate GH, or by a decreased number of GH receptors on tissues (down-regulation). These are theoretical concerns as no long-term studies have been undertaken to clarify the issues.
Side effects of CJC-1295 may include injection site reactions (irritation, erythema, induration, pain, itching), headache, diarrhea, vasodilation (flushing, warmth, transient hypotension), nausea, abdominal pain. | This peptide CJC-1295 CJC-1295 W-DAC 2MG is also an artificial growth hormone. This is one of the best hormone because of its versatility and can be used in muscle build-up, weight gain, weight loss, anti-aging, and increasing in growth hormones. Take this from 0.5mg-2mg per week 20 at anytime of the day. Inject this 20 minutes prior to eating.
| Trenbolone Enanthate – injectable steroid that is used mainly in bodybuilding and weightlifting to achieve maximum growth of compacted muscle mass and a significant increase in power capacity.
Trenbolone Enanthate ester is characterized by a long period of exposure into the body (about six weeks).
Trenbolone Enanthate Effects
significant increase in muscle mass (average 10 kg per 8 weeks);
increasing the degree of endurance and power performance;
200% increase in the level of insulin-like growth factor stimulation and hyperplasia of the muscle;
fat burning effect (including the influence due to the release of growth hormone);
lowering cortisol levels (a hormone which facilitates the destruction of proteins, increased fat accumulation and glucose).
How to Use Trenbolone Enanthate: Dosage, Cycle, PCT
To create a cycle for Trenbolone Enanthate, which also would be effective and safe for the body, stick to a few rules:
Do not exceed the dosage of the drug and duration of the cycle (the optimal dose of Trenbolone Enanthate per week – 300 mg, cycle length – 6-8 weeks).
Always start with a minimum rate of injection to fix the body’s response to anabolic effects.
Take Gonadotropins, if the steroid cycle is designed for 5 weeks and more.
Do not neglect the power of sports complex and a special diet for weight gain.
Always consult a doctor before starting the cycle.
Trenbolone Enanthate Combination Cycles
Trenbolone Enanthate, to gain muscle mass, is often taken solo, because of its efficiency. In professional cycles at a dosage of 250 mg per week, can be stacked with Testosterone Enanthate, but this combination is only valid for the experienced athletes, and after a medical advice.
For drying period one can buy Winstrol, or Anavar without anti-estrogens, using half of the dosage.
As PCT on Trenbolone cycle is used Toremifene or Clomid.
Trenbolone Enanthate Reviews
After analyzing published on Trenbolone Enanthate reviews, it is easy to draw a conclusion about the quality of weight and severity of the effect: more than 90% of athletes and bodybuilders were satisfied with the results of the cycle. The absence of the phenomenon of rollback and flavoring also played a significant role in relation of athletes with this steroid.
Warnings: Keep out of reach of children. For adults only. | Ipamorelin is a pentapeptide and a ghrelin mimetic with growth hormone releasing activity.
Ipamorelin imitates ghrelin and ties to the ghrelin receptor in the brain, thus selectively stimulating the release of growth hormone from the pituitary gland.
Usage
Growth hormones are frequently released and more abundant in children. When humans begin to age, the production of growth hormones decelerates and lessens gradually over time. The use of Ipamorelin can encourage these growth hormones to be created and released regularly.
Ipamorelin is used to help increase growth hormone production, which can assist in the reduction of body fat, enhancement of lean muscle mass, improvement of sleep, and increase of energy and over all wellness.
Ipamorelin is mostly used for collagen production, wrinkle reduction, acceleration of healing and recovery, and enhancement of mood and sleep; therefore being a peptide that is sought after for it’s anti-aging benefits.
Mechanism of Action
The function of Ipamorelin is to mimic ghrelin. The hormone ghrelin, discovered in 1999, has extreme effects on metabolism, restraining stored fat breakdown, and most importantly gherlin performs to regulate growth hormone release from the pituitary gland.
Ipamorelin fastens to ghrelin receptors on the pituitary gland, activating them identically to the way ghrelin naturally would. The activation of these receptors work collectively with no effect on the rest of the body’s hormones.
Administration
Mode of Administration: Subcutaneous injection to a fleshy part of the body, typically to the stomach or abdominal area.
Before administering Ipamorelin, always be sure to use a clean and sterile syringe.
Hold the Ipamorelin vial upright and insert the syringe in the center of the cap.
Draw the plunger until you have the correct amount (see ‘Dosage’ below) in the syringe and carefully remove it.
Before administering the syringe, use alcohol to cleanse the area of skin.
Pinch the skin around the area to be injected, leave about 2 cm on each side.
Hold the syringe at a 90 degree angle to your skin and swiftly insert the syringe.
Depress the plunger fully, until the syringe is empty, and carefully draw out.
Dosage
Dosage Amount: 100mcg - 500mcg (0.1mg to 0.5mg)
Dosage Frequency: 1-3 times daily
Recommended dose of 300mcg, 3 times daily (injection under the skin) for strength gain and performance enhancement
Recommended dose of 200mcg, 1 time daily (injection under the skin) for anti-aging purposes
For best results, it is recommended to administer Ipamorelin at the same time daily. Avoid consumption of food and liquids at least one hour before and after administering Ipamorelin.
Expectations
Ipamorelin typically takes time to show results. While some patients will notice significant changes in the body after the first month, the full-benefits are usually noticed after three to six months of administering the peptide daily.
Ipamorelin is most successful with diet, exercise, consistency and time.
Side Effects
The most common reaction to Ipamorelin is redness and irritation around the injection site. This reaction is typically short term and normally goes away on its own.
Ipamorelin is can also increase hunger and cause dry mouth in some patients.
In less than 1% of patients that use Ipamorelin, other side effects have occurred, including: severe drowsiness, hives, vomiting, headache, nausea, difficulty swallowing, hyperactivity, chest tightness and pallor, distortion in perception of taste, and flushing of the skin.
Benefits
Anti-aging: collagen production and wrinkle reduction
Increase of lean muscle mass and muscle growth
Accelerated recovery time from exercising, weight lifting and physical activity
Improvement in cellular repair and regeneration
Increase of energy, the immune system and overall wellness
Improvement in bone strength and bone mineral density composite
Higher metabolic rate and improved circulation resulting in body fat reduction
Improvement in sleep cycle, resulting in heightened mood and energy | Eurigil (HCG) 5000IU is an injectable drug manufactured by Euro-Pharmacies and containing as active substance Human Chorionic Gonadotropin (hCG). This is a hormone produced during pregnancy that is made by the developing placenta after conception, and later by the placental component syncytiotrophoblast. One of the uses of hCG is to suppress hunger and trigger the human body’s use of fat for fuel. hCG is used also to cause ovulation and to treat infertility in women, and to increase sperm count in men. bodybuilders use it in steroids cycles and in post cycle therapy to lose gain and to increase Testosterone production.
Eurigil (HCG) 5000IU is utilized among bodybuilders and athletes at the end of an anabolic-androgenic steroid cycle to prevent the breakdown of muscle tissue. It is also important in restoring the testes to the normal abilities. Many times after a period of anabolic steroids usage the testes of an athlete may shrink. Pregnyl is effective in returning them to normal size. When used along with a very low-calorie diet, athletes burn off that extra fat over their muscle mass. Females may also use Pregnyl with a very low calorie diet to burn off unnecessary fat.
The average dosage of Eurigil (HCG) 5000IU during a cycle is between 500iu to 3000iu every week (1-3 times per week). If the injection is taken more frequently the blood level of the athlete are more stable while taking it in one shot may increase the estrogen levels caused by the aromatization of normal Testosterone and result in gynecomastia. There are sources showing that some bodybuilders used 6000iu for 6 days, but this is a risky affair and depend on the individual features of men. As post cycle therapy Pregnyl should be used in smaller doses, about 250 – 500iu every day for 2 or 3 weeks. Smaller doses are enough to begin reversal process of testicular atrophy. When starting a cycle of hCG, bodybuilders must follow it for 2 to 3 week range with a least one month off in between and follow this course with no concern. Pregnyl can be used with Clomid or Nolvadex in the PCT and continue using them after HCG is no longer part of the cycle. It is also recommended to start and hCG cycle near the end of a normal steroids cycle, most effective in the last week.
The most serious side effects that may occur while using Eurigil (HCG) 5000IU are: severe pelvic pain, swelling of the hands or legs, stomach pain and swelling, shortness of breath, weight gain, diarrhea, nausea or vomiting. Other common side effects of Pregnyl are: headache, feeling restless or irritable, mild swelling or water weight gain, depression, breast tenderness or swelling; or pain, swelling, or irritation where the injection is given. Among boys the medicine can cause early signs of puberty, such as a deepened voice, pubic hair growth, and increased acne or sweating. | Insulin-like growth factor-1 (IGF-1) helps encourage normal bone and tissue growth and development and also has the ability to decrease blood glucose levels.
IGF-1 advances to fat cells and therefore burns fat. Subsequently, it increases lean body mass and decreases fat. These effects are desired mostly by athletes and bodybuilders. Increased IGF-1 levels are also comparable to weight gain. This weight gain is a result of lean body mass growth, not fat production.
IGF-1 is favored in the bodybuilding industry and for people who workout regularly. It helps enhance recovery time after workout and improves energy during the workout.
IGF-1 injections are common for adults and children if they have a growth hormone deficiency. IGF-1 contains many necessary amino acids that can help children who are not developing at a standard rate and supplement adults that are deficient.
Research has also shown that the anabolic effects of IGF-1 may reflect inhibited protein breakdown and stimulated protein synthesis in skeletal muscle and that this response may be caused by a direct effect of IGF-1 on muscle tissue, therefore assisting burns on the skin and other tissue abnormalities.
Mechanism of Action
IGF-1 is a hormone found naturally in human blood. Its primary function is to manage the effects of growth hormone in the body. Normal IGF-1 and growth hormone functions include tissue and bone growth. IGF-1 is formed in different tissues as a result of growth hormone in the blood.
IGF-1 promotes systemic body growth, and has growth-stimulating effects on mostly every cell in the body, mainly bone, cartilage, skeletal muscle, liver, kidney, nerve, skin and lung cells. As well as the insulin-like effects, IGF-1 can also manage cellular DNA synthesis.
Administration
Mode of Administration: Subcutaneous injection to a fleshy part of the body, typically to the stomach or abdominal area. IGF-1 can also be administered intramuscularly.
Before administering IGF-1, always be sure to use a clean and sterile syringe.
Hold the IGF-1 vial upright and insert the syringe in the center of the cap.
Draw the plunger until you have the correct amount (see ‘Dosage’ below) in the syringe and carefully remove it.
Before administering the syringe, use alcohol to cleanse the area of skin.
Pinch the skin around the area to be injected, leave about 2 cm on each side.
Hold the syringe at a 90 degree angle to your skin and swiftly insert the syringe.
Depress the plunger fully, until the syringe is empty, and carefully draw out.
Dosage
Dosage Amount: For lean muscle growth and fat loss
40 mcg - 50 mcg daily (men)
10 mcg - 20 mcg daily (women)
IGF-1 should not be injected more than twice daily
A typical dosage cycle of IGF-1 will continue for 2 to 12 weeks
Children and adults who are prescribed IGF-1 for development deficiency should consult with a care provider about correct dosing.
Side Effects
The side effects of IGF-1 can be similar to those of other growth hormones. These include growth of excess body tissue, also known as acromegaly, and damage to the joints, liver, and heart. IGF-1 could possibly cause joint pain, muscle pain, headaches and nausea. IGF-1 can also decrease levels of blood glucose, resulting in hypoglycemia. Researchers also associate IGF-1 with an increased risk of developing some cancers, such as lung, breast, colorectal and prostate.
Benefits
Facilitation of protein synthesis in the body
Regulation of stored fat and channeling it to be used for energy production, resulting in fat loss
Promotion of positive effects on metabolism and increasing lean body mass and muscle growth
Protection against autoimmune disease, heart disease and plaque buildup
Aid development in young children and adults deficient in essential amino acids
Improvement in blood sugar regulation
Promotion of optimal health, wellness and fitness in users |
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