|Content||Hexarelin, also known as Examorelin and Hexarelin Acetate, is a potent, synthetic hexapeptide and a highly selective agonist (initiates a physiological response when combined with a receptor) of the ghrelin/growth hormone secretagogue receptor and a growth hormone secretagogue.
Hexarelin is used to stimulate natural growth hormone production, promoting lean muscle growth, rapid fat loss, increased tendon and ligament strength, enhanced flexibility, and better recovery from injuries and training sessions.
By increasing natural growth hormone levels, Hexarelin also enhances production of Insulin-like Growth Factor 1 (IGF-1) in the body. This further drives the growth of lean muscle tissue, improving strength and body composition. Likewise, Hexarelin promotes significant gains in athletic performance, preventing musculoskeletal injury while reducing recovery time between training sessions. In addition, its method of action prevents many of the negative side effects of synthetic hGH administration, including the shutdown of natural growth hormone production
Mechanism of Action
Growth hormone is made and released by the pituitary gland. Hexarelin functions to enhance the natural growth hormone production by amplifying the natural growth hormone releasing signal. This results in a greater secretion of growth hormone from the pituitary gland. Hexarelin then suppresses a hormone in the body called somatostatin, also known as growth hormone inhibiting hormone. Somatostatin causes the body to reduce its natural growth hormone output. By limiting the action of somatostatin, growth hormone production is escalated, resulting in significantly increased natural growth hormone levels.
Hexarelin can bind to and activate the growth hormone secretagogue receptor in the brain similar to its natural counterpart ghrelin. Hexarelin has been studied to be much more potent and stable than gherlin.
The outlying distribution of growth hormone secretagogue in the heart and blood vessels suggests that Hexarelin may have direct cardiovascular actions beyond growth hormone release and neuroendocrine effects.
Mode of Administration: Subcutaneous injection to a fleshy part of the body, typically to the stomach or abdominal area. Hexarelin can also be taken orally.
Before administering Hexarelin, always be sure to use a clean and sterile syringe.
Hold the Hexarelin vial upright and insert the syringe in the center of the cap.
Draw the plunger until you have the correct amount (see ‘Dosage’ below) in the syringe and carefully remove it.
Before administering the syringe, use alcohol to cleanse the area of skin.
Pinch the skin around the area to be injected, leave about 2 cm on each side.
Hold the syringe at a 90 degree angle to your skin and swiftly insert the syringe.
Depress the plunger fully, until the syringe is empty, and carefully draw out.
Dosage Amount: 200mcg - 300mcg daily, administering 100mcg at a time
Hexarelin is generally administered 2-3 times daily at dosages of 100mcg per administration. As Hexarelin is best suited for athletic performance enhancement rather than anti-aging purposes, it is commonly administered at least 2 times per day to increase growth hormone as much as possible in the limited duration of a cycle (up to 16 weeks). These dosages provide a substantial increase in growth hormone output to facilitate muscle growth, strength gain, fat loss, and recovery from training and injury. For best results, it is recommended to avoid eating one hour before and after administering Hexarelin.
Common side effects of Hexarelin can include feelings of tiredness or lethargy, as growth hormone can increase the desire for sleep as well as its quality and restorative capabilities. Although Hexarelin is a growth hormone releasing peptide, it does not stimulate an increase in appetite through increased ghrelin activity.
Excess dosages may lead to water retention as well as tingling or numbness in the hands and feet. This can be a sign that the dosage is too high and should be reduced. Hexarelin may have a stimulatory effect on adrenocorticotropic hormone (ACTH), cortisol, and prolactin. Though not an issue for the vast majority of users, this may cause interactions with certain medications or unwanted effects in individuals with certain health conditions.
Increase growth of lean muscle
Acceleration of weight loss/ fat loss
Increase of tendon and ligament strength
Enhancement of flexibility and joint health
Promotion of quicker recovery from injuries and training
Resistance to musculoskeletal injury
Improvement of sleep quality
Enhancement of athletic performance and physical capacity||Oxytocin is a hormone secreted by the posterior lobe of the pituitary gland, a pea-sized structure at the base of the brain.
It's sometimes known as the "cuddle hormone" or the "love hormone," because it is released when people snuggle up or bond socially. Even playing with your dog can cause an oxytocin surge, according to a 2009 study published in the journal Hormones and Behavior. But these monikers may be misleading.
Oxytocin can also intensify memories of bonding gone bad, such as in cases where men have poor relationships with their mothers. It can also make people less accepting of people they see as outsiders. In other words, whether oxytocin makes you feel cuddly or suspicious of others depends on the environment.
Oxytocin in women
Oxytocin is a particularly important hormone for women. "Oxytocin is a peptide produced in the brain that was first recognized for its role in the birth process, and also in nursing," said Larry Young, a behavioral neuroscientist at Emory University in Atlanta, Georgia.
The hormone causes uterine contractions during labor and helps shrink the uterus after delivery. When an infant suckles at his or her mother's breast, the stimulation causes a release of oxytocin, which, in turn, orders the body to "let down" milk for the baby to drink.
Oxytocin also promotes mother-child bonding. Studies show that "female rats find pups to be aversive if [the females are] virgins," Young told Live Science. "But once they give birth, the brain is transformed, so they find the pups irresistible," he said. And similar findings are seen in humans.
A 2007 study published in the journal Psychological Science found that the higher a mom's oxytocin levels in the first trimester of pregnancy, the more likely she was to engage in bonding behaviors such as singing to or bathing her baby. [11 Interesting Effects of Oxytocin]
Although maternal bonding may not always be hardwired — after all, human females can adopt babies and take care of them — oxytocin released during pregnancy "does seem to have a role in motivation and feelings of connectedness to a baby," Young said. Studies also show that interacting with a baby causes the infant's own oxytocin levels to increase, he added.
Oxytocin in men
In men, as in women, oxytocin facilitates bonding. Dads who got a boost of oxytocin via a nasal spray played more closely with their 5-month-old babies than dads who didn't get the hormone zap, a 2012 study found. (There is another hormone, called vasopressin, which plays a stronger role in men.)
This anti-social effect of a social hormone brings some nuance to the story of oxytocin. In one study, researchers found that Dutch students given a snort of the hormone became more positive about fictional Dutch characters, but were more negative about characters with Arab or German names. The finding suggests that oxytocin's social bonding effects are targeted at whomever a person perceives as part of their in-group, the researchers reported in January 2011 in the journal PNAS.
In another study, published in PNAS in 2010, men were given a dose of oxytocin and asked to write about their mothers. Those with secure relationships described their moms as more caring after the hormone dose. Those with troubled relationships actually saw their mothers as less caring. The hormone may help with the formation of social memories, according to the study researchers, so a whiff strengthens previous associations, whether good or bad.
"My view of what oxytocin is doing in the brain is making social information more salient," Young said. "It connects brain areas involved in processing social information — whether it's sights, faces, sounds or smells — and helps link those areas to the brain's reward system."
Oxytocin sprays and side effects
Oxytocin nose sprays also have been considered for use in treating autism. The neurological disorder is marked by struggles with social functioning, so a small 2013 study published in the journal PNAS gave a dose to children and teens with autism and asked the participants to identify emotions based on pictures of people's eyes.
The participants weren't any better at identifying the emotions after the oxytocin burst, but the regions of their brains associated with social interaction became more active. The increased processing could mean that a burst of oxytocin might help cement behavioral therapy for kids with the disorder.
"When you think about using oxytocin to treat diseases like autism, you want to make sure you do it in a context where the social information is positive," Young said.
Use of oxytocin sprays outside of a medical context is far murkier, however. The sprays sold online without a prescription promise stress relief and social ease, but they are not regulated by the Food and Drug Administration (FDA). That means that nothing is known about their efficacy, side effects, or even whether they contain any oxytocin.
There are no long-term studies on the side effects of the legitimate oxytocin sprays used in hormone research; most studies give people one dose of the hormone only. Pitocin, a synthetic version of oxytocin given intravenously to stimulate labor, has side effects that include nausea, vomiting and stomach pain.||Melanotan II analog of alpha-melanocyte stimulating hormone (a-MSH). Melanotan peptides are safe and efficacious with growing long term data. Melanotan 2 is a freeze dried peptide sealed in a sterile multi-use vial. Tanning injections of synthetic potent a-MSH allow for development of photo-protective suntans in all skin types.
Melanotan 2 Dosage
Range: 100mcg – 1mg
Melanotan II Side Effects
Melanotan injections act on melanocytes to stimulate melanin production. Melanin is the body’s pigment responsible for a photoprotective safe tan.
Sunless tanning injections begin with the peptide sequence: His-Phe-Arg-Trp. Melanotan peptides Melanotan II binds to melanocortin receptors influencing pigmentation, inflammation, energy, appetite and sexual function. Melanotan 2 has a small protective amino acid structure that effects the melanocortin 1, 3, 4 and 5 receptors.
Melanotan 2 Peptide Hormone
Melanotan 2 is a small efficient molecule as compared to the linear original Melanotan I design after natural melanocyte stimulating hormone peptide. Melanotan is approximately 1,000 times more potent than natural a-MSH. Melanotan half life of minutes, Melanotan 2 half life ~1 hour.
Melanin skin tanning after Melanotan injection
Folks who never tan, always burn in the sun, can achieve a natural tan when using Melanotan II. For people with sun allergies/mutated receptors, synthetic melanotropin peptide supplements offer life changing opportunity. A natural tan developed over time is the best defense against cancer, to which the fair skin can now acheive. Melanotan was designed to reduce cancer rates and potentially become effective as a sunless tanning agent.
Fitzpatrick skin type: Skin type I and II, the lower of the skin types on the Fitzpatrick scale are the best candidates for Melanotan.
Athletes and fitness enthusiasts use Melanotan for accelerated tanning, libido increase and appetite suppression. Melanotan 2 was dubbed the Barbie drug and has been highlighted in wired magazine. Synthetic melanocortin therapy helps attain a tan with the least amount of exposure to harmful ultraviolet radiation. Melanotan II continues to be the most effective tanning peptide sold online.
Fitzpatrick Skin Type Description
I Extremely fair skin, always burn, never tans.
II Fair skin, always burns, sometimes tans.
III Medium skin, sometimes burns, always tans.
IV Olive skin, rarely burns, always tans.
V Moderately pigmented brown skin, never burns, always tans.
VI Markedly pigmented black skin, never burns, always tans.
Peptide Hormone Therapy: Melanotan stimulates melanin, particularly low fitzpatrick types.
Disclaimer: Please pursue information regarding the usage of these products from your own research, academic journals, or the research of your in-house scientific team. Products sold for research purposes are not for human consumption. Melanotan Peptides are not known to contain filler (mannitol).
review melanotan results chart melanin density after tanning injections
Reconstituted with bacteriostatic water, Melanotan 2 research peptide remains potent and preserved. Reconstituting Melanotan 2 peptide is a necessity and will require proper due diligence for results. Nasal sprays, pre-mixed Melanotan 2, pills, oral melanotan2 are not legitimate. Enzymes will render the peptide inactive if ingested. Purchase only pure Melanotan II custom synthesis.
Melanotan Shipping: Melanotan peptides are durable and stable. Shipping in the summer not a problem for tanning melanocortins. When receiving MT-2 it is recommended to store in the refrigerator. Save money and do not pay for cold melanotan 2 shipments. Further, do not store Melanotan 2 in freezer.
Mixing Melanotan 2: 1-2ml Bacteriostatic water reconstitutes and preserves tanning peptide Melanotan best. Dilute with more volume for improved dosing accuracy (micrograms).
Dosage Calculator: Add 100 units (1ml) of water to the vial. 1ml Bacteriostatic water will minimize injection volume and simplify arithmetic. Dosing measurements are often mentioned in both milligram (mg) and microgram (mcg).
1ml syringe (U100), 1ml Bac Water to Reconstitute
Calculations for .5mg or 500mcg dose:
Step 1 1ml
Step 2 10mg Melanotan II
Step 3 1ml Bacteriostatic Water
Step 4 500mcg Dose
5 units on your insulin syringe (approximately 1/20th of a U100 syringe).
Needles: 29-31 gauge X 1/2″, 1 CC (100 unit). That is a typical insulin needle used to mix as well as inject. Use needles one time only. Once your technique perfected, injections are almost painless. Smaller 1/2 and 1/3cc syringes offer greater measurement accuracy and pre-loading convenience.
Melanotan Dosage: Your first injection should be a very small dose, for example .25mg (250mcg). See how you react. Goal should be to feel nothing. Dose after dinner, before bed. Any dosing chart stating that you should take a high dose (according to your weight) is dated and potentially dangerous.
Loading dose: Load with .5-1mg once a day. People who have used doses in this range generally report getting excellent results. Don’t worry if you miss occasional days. It will not make much difference, focus on the cumulative effects. A tan generally sets in 3 days after UV rays. Dose and expose yourself gradually to UVR when tanning.
Maintenance dosing: Maintenance is taking doses less frequently than daily to avoid becoming darker than you want. Yes, that will happen. With enough UVR, you will get much darker than you have even been before. A maintenance dose can help prolong super-physiological photo-protection MT-2 delivers.
UV Radiation: Melanotan is a poor sunless tanner. UV (from sun or a tanning bed) light is necessary to develop a tan for most folks. Without it, almost nothing happens. In other words, NO UV = NO TAN. Melanotan use for a full month and with UV exposure, you (and your friends) will be astounded by how fast and how dark MT-II tanning results. Areas of skin that are typically sun-exposed in your day to day life will respond more readily to the effects of the melanotan peptides, take photo therapy serious with Melanotan II.
Melanotan 2 Weight Loss: Melanotan II peptide usage results in adipocyte lipolysis. Dose low-moderate between meals to increase fatty acid oxidation, reduce food intake, and increase energy.
Side-effects of Melanotan II
Possible short-term side effects include: nausea, appetite loss, facial flushing and increased libido. Melanotan side effects may be noticeable during the first few days of treatment but should taper off as the body desensitizes.
Do you have to inject Melanotan Peptides?
Yes. The best, most efficient method of administering Melanotan peptides are subcutaneous (subq) injection. Nasal sprays are inconsistent and inefficient at best. No detectable levels were observed following oral melanotan dosing.
Note: There are many things you will need to consider before experimenting with melanotans peptide. Cyclic analogues (Melanotan II) have a wide range of peripheral effects and systemic control is always going to pose an issue in clinical research. Needless to say, Melanotan2 is not an approved or regulated product. Melanotan is legal to buy, possess, etc.
When supplementing Melanotan to tan keep in mind that tanning is literally a side effect. The tanning response is, in reality, a physiological repair mechanism to UV damage of the cells (epidermis/dermis). Melanocyte stimulating hormone is not going to color your skin, it is going to make your own cells create its own tan and that in turn creates protection. If you are looking to be some bronzed beach God with perfectly uniform and specific color then you are better off to going to mystic tan. Redheads, for example, naturally produce a variant form of melanin that is yellowish-red (pheomelanin). Do not expect a brown tan on ginger skin without serious diligence.
Melanotan Dosage: Knowing your skin type is one detail which will help create a public user log. There are thousands of melanotan users worldwide who share the experience. Raise awareness and help others who want to hear success stories, complications and failures.
Am I a candidate for Melanotan?
Melanotan is best suited for the folks with skin types I & II. Prior sun damage, scars, tattoos, freckles, moles, hair color, etc are deciding factors prospective MT-2 users consider.
How should I dose Melanotan II?
Melanotan II dosage it is recommended to start out small and build up. A typical starting dose is around .25mg and max dose reaching 1mg. Desensitization happens quick, the first administration is an opportunity to dose low to avoid Melanotan 2 side effects. Same goes for bremelanotide (PT-141) dosage unfortunately.
Melanotan Instruction: There is no magic pill or formula. Instructions do not exist for research peptides. Few dermatologists are familiar with Melanotan. The skin is a large, unpredictable organ. Feel comfortable and confident with MT-II before use. Check out as many before and after photos and user logs as you can. A skin type I individual may have to commit months of dedication before dialing in their desired results, be patient and ask questions.
How much Melanotan peptide should I purchase?
Skin Type Dosage
Skin Type I 30-50mg
Skin Type II 20-30mg
Skin Type III 10mg
Should last entire summer or season.
How soon will I see Melanotan results? Change in tone after 2-3 weeks should be anticipated. If you have freckles, expect them to get darker before your actual skin color changes. Brace yourself, within days Melanotan will.
How long will my tan last? A tan developed using Melanotan 2 lasts much longer than an ordinary tan. A well-tanned person returning from a beach holiday will lose most of the tan in a month if they stop getting sun. But if they had been using Melanotan 2 and continued on maintenance after returning, they would still have most of their tan 3 months later.
The information presented on this web site is not intended to take the place of your personal physician’s advice and is not intended to diagnose, treat, cure or prevent any disease.||Trenbolone Enanthate – injectable steroid that is used mainly in bodybuilding and weightlifting to achieve maximum growth of compacted muscle mass and a significant increase in power capacity.
Trenbolone Enanthate ester is characterized by a long period of exposure into the body (about six weeks).
Trenbolone Enanthate Effects
significant increase in muscle mass (average 10 kg per 8 weeks);
increasing the degree of endurance and power performance;
200% increase in the level of insulin-like growth factor stimulation and hyperplasia of the muscle;
fat burning effect (including the influence due to the release of growth hormone);
lowering cortisol levels (a hormone which facilitates the destruction of proteins, increased fat accumulation and glucose).
How to Use Trenbolone Enanthate: Dosage, Cycle, PCT
To create a cycle for Trenbolone Enanthate, which also would be effective and safe for the body, stick to a few rules:
Do not exceed the dosage of the drug and duration of the cycle (the optimal dose of Trenbolone Enanthate per week – 300 mg, cycle length – 6-8 weeks).
Always start with a minimum rate of injection to fix the body’s response to anabolic effects.
Take Gonadotropins, if the steroid cycle is designed for 5 weeks and more.
Do not neglect the power of sports complex and a special diet for weight gain.
Always consult a doctor before starting the cycle.
Trenbolone Enanthate Combination Cycles
Trenbolone Enanthate, to gain muscle mass, is often taken solo, because of its efficiency. In professional cycles at a dosage of 250 mg per week, can be stacked with Testosterone Enanthate, but this combination is only valid for the experienced athletes, and after a medical advice.
For drying period one can buy Winstrol, or Anavar without anti-estrogens, using half of the dosage.
As PCT on Trenbolone cycle is used Toremifene or Clomid.
Trenbolone Enanthate Reviews
After analyzing published on Trenbolone Enanthate reviews, it is easy to draw a conclusion about the quality of weight and severity of the effect: more than 90% of athletes and bodybuilders were satisfied with the results of the cycle. The absence of the phenomenon of rollback and flavoring also played a significant role in relation of athletes with this steroid.
Warnings: Keep out of reach of children. For adults only.||GHRP-6 peptide which is structurally very similar to its predecessor, GHRP-2 The main difference is that the GHRP-6 increases appetite in some people. Both peptides can be used together to achieve better synergistic effects. Studies have shown that the highest concentrations of growth hormone in the blood is achieved just combinations of GHRP-6 and GHRP-2. GHRP-6 stimulates the pituitary gland to produce GH. GHRP can be effectively used in the treatment of growth hormone deficiency. GHRP-6 is highly effective in increasing blood levels of the hormone HGH and IGF-1.
GHRP-6 stimulates and strengthens the immune system, has a strong anabolic – for massive muscle gains and strength, helps burn body fat, has a very strong anti-aging effect, smooths wrinkles, improves the condition of hair and skin, gives a very good sleep and excellent regeneration, increases bone strength, has anti-inflammatory effects, brings a sense of the large influx of energy and vitality, and causing general overall rejuvenation of the body and all of its body tissues.
GHRP-6 helps very effectively to gain muscle mass, increase strength, recovery and burn fat. GHRP-6 improves energy metabolism.
Combining GHRP 6 with CJC 1295
The combined use of CJC 1295 peptide without DAC can greatly enhance its results in conjunction with GHRP 6.
Combining GHRP 6 with T3
The efficiency of GHRP 6 can greatly amplify with little high levels of T3 in the body.||During any physical work the body produces insulin-like growth factor. It leads to the appearance of a large number of muscle cells causing muscle growth. In addition this substance helps to accelerate the healing process. One of the types of this hormone is a peptide Peg MGF. It is similar to growth hormone because of its characteristics but the main difference is that it does not affect the ligaments and cartilage condition.
An active substance MGF has a very short half-life. To increase the effectiveness of the hormone it is possible to create a kind of capsule consisting of polyethylene glycol surrounding the hormone. The human’s body does not react to polyethylene glycol and the transit time of the hormone in the organism can be increased. With this solution Peg MGF peptide has a long lasting effect allowing you to achieve your goals.
Peg MGF feedbacks show that this peptide is especially popular among young athletes. It has been proved that the peptide has less effect on elder people so it depends on the age of the athlete. Researches show that the full course allows to increase muscle size by 15%.
The effects of Peg MGF
It is recommended to buy Peg MGF when you need to:
increase the growth of muscle tissue;
reduce the number of fat cells in the body;
increase endurance and strength;
achieve an apparent muscle relief;
accelerate the recovery of muscle cells after workout or injury;
achieve detailed venous pattern;
stimulate the formation of new venous branches.
In the addition to the above points, Peg MGF improves immune forces of the body, lowers cholesterol level in blood, strengthens the nervous system, stimulates the formation of bone marrow cells, improves skin and prevents the negative impact of the increased heart stress.
Application and dosage of Peg MGF
The peptide can be administered in two ways. In first case the dosage for Peg MGF is from 100 to 200 mcg. Preparation can be administered every 2-3 days during 5 or 6 weeks. Then the pause for 3 weeks must be made. It is recommended to inject the peptide immediately after workouts. The course is repeated if necessary until the desired result is achieved.
Side effects and contraindications
Before beginning a hormone course you must carefully read the instructions for the use of Peg MGF. In rare cases there are possible some complications such as increased growth and size of limbs and prostatic hyperplasia. So peptide administration is allowed under the careful attention of experienced professionals and after consulting a doctor.|