| Content | Letrozolexin is a nonsteroidal inhibitor of estrogen synthesis with antineoplastic activity. As a third-generation aromatase inhibitor, Letrozolexin selectively and reversibly inhibits aromatase, which may result in growth inhibition of estrogen-dependent breast cancer cells.
Aromatase, a cytochrome P-450 enzyme localized to the endoplasmic reticulum of the cell and found in many tissues including those of the premenopausal ovary, liver, and breast, catalyzes the aromatization of androstenedione and testosterone into estrone and estradiol, the final step in estrogen biosynthesis.
Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding to the heme of its cytochrome P450 unit. The action is specific, and letrozole does not reduce production of mineralo- or corticosteroids. In contrast, the antiestrogenic action of tamoxifen, the major medical therapy prior to the arrival of aromatase inhibitors, is due to its interfering with the estrogen receptor, rather than inhibiting estrogen production.
Letrozolexin is approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women. Side effects include signs and symptoms of hypoestrogenism. There is concern that long term use may lead to osteoporosis, which is why prescriptions of Letrozolexin are often accompanied by prescriptions of osteoporosis-fighting medication such as Fosamax.
Letrozolexin has shown to reduce estrogen levels by 98 percent while raising testosterone levels.
The anti-estrogen action of Letrozolexin is preferred by athletes and bodybuilders for use during a steroid cycle to reduce bloating due to excess water retention and prevent the formation of gynecomastia related breast tissue that is a side effect of some anabolic steroids. Usage above 2.5 mg/day is known to potentially temporarily kill sex drive. Above 5mg/day for extended periods may cause kidney problems.
Letrozolexin has also been shown to delay the fusing of the growth plates in adolescents. This may boost the effectiveness of growth hormone, and thus Letrozolexin is used to treat adolescents and children with short stature. | What is Clomiphene ?
These steroids online are used to medicate infertility in women. Clomiphene has been seen to stimulate the body to churn out gonadotrophic hormones to realign its testosterone levels to prevent a catabolic state from taking place. It does this by encouraging the hypophysis or anterior pituitary gland to work double time after cycling with prohormones and anabolic steroids. It helps in stimulating increase in the production of hormones that support the growth and release of a mature egg during ovulation. However, this drug is not recommended for female whose ovaries are not making healthy eggs properly or those that have pituitary and ovarian failure.
How to Use It
To make this drug to be most effective, follow the instructions exactly as directed by the doctor. If people buy steroids online, it should be taken the same time daily and with the proper dosage. Medication should not last more than 6 cycles.
Dosage should be based on your medical condition and how your response to therapy. Avoid taking it more often or longer than prescribed by the physician. Your physician may ask you to record your body temperature and other vital signs and other symptoms for best monitoring
If you buy steroids online, keep it out children's reach and avoid exposure from direct sunlight, heat and, moisture. Buy steroids and safely discard when it reached its expiry date by following the instructions from your physician.
Buy steroid and check other injectable steroids for sale for more options. | Product Description
Tamoxifen Citrate is another medication you can buy steroids online. It is used for the treatment of breast cancer. It is used to reduce the chances of breast cancer in high-risk patients. It also blocks the growth of breast cancer. It interferes with the effects of estrogen in the breast tissue.
Dosage and Administration
Take Tamoxifen Citrate by mouth with or without meals when you buy steroids online. It is usually taken once or twice daily for 5 years or as directed by the physician. Daily dosages of more than 20 mg are divided in half and taken twice daily, in the morning and evening, or as directed by the physician.
The duration of the treatment to prevent cancer from relapsing may be between 5 to 10 years. This still depends on your condition and response to treatment.
Contraindications and Precautions
Numb/tingling skin, headache, hair thinning, muscle aches, leg cramps, nausea, and hot flashes may occur. A loss of sexual interest and ability may occur in men. If these symptoms worsen, tell your doctor immediately. | | What is KETOTIFEN FUMARATE?
Bodybuilders used Ketotifen as an antihistamine drug for treating allergy symptoms and asthma management. The substance beta-2 receptor properties of ketotifen make this medication an interest to bodybuilding and athletic community. Beta-2 receptor supports fat loss, although not a strong fat loss compound by itself. But when taken with Clenbuterol, it may increase thermogenic potency and noticeably extend the active lipolysis. Moreover, ketotifen extend the effectivity of other steroids when used for several weeks for a therapy.
Common side effects of this steroid include dry mouth, appetite stimulation, weight gain, dizziness, and drowsiness. You can noticed that all of this side effects are commonly associated with strong antihistamine drug.
How to use it?
Bodybuilders and athletes commonly use a dosage of steroids online of 1mg twice a day for the use of preventing receptor downregulation with Clenbuterol. This may allow the person taking it to gain a strong thermogenic effect from and run longer cycles. Note that given its property to increase drug sensitivity, the dosage of beta-2 agonist medications might need to be lessen upon the administration of ketotifen.
However, always remember not to take steroids online or other medications if you are pregnant for the cases of women. The doctor must regularly examine you for this possibility. Tell your doctor all of your health conditions as there may some interactions with your current medication of steroids online. Importantly, they should extra supervise you in case you have an existing condition. Lastly, only the doctor or a nurse can administer these steroids online. Your dose depends on your condition and your doctor will decide the dosage.
Browse other Peptides, Ancillaries and check the different types of supplements HERE. | What is LEVOTHYROXINE?
Our thyroid gland produces a naturally occurring hormone called levothyroxine- also known as T4. The thyroid hormones in the body consists in the regulation of burning fat, carbohydrates and protein. They are responsible for the amount of the metabolic turnover, which is burned in the resting state during a given period of time. Bodybuilders occasionally use this during the mass phase, to increase the metabolic turnover and burn more calories. Furthermore, bodybuilders take protein preparations and/or Clenbuterol with the use of this hormones to counteract the muscle breakdown.
Side effects include trembling, restlessness, dizziness, sweating, weight gain, hair loss, diarrhea, insomnia, nausea, increased heart rate etc.
How to Use it?
Athletes speak of dosages between 200-400 mcg/day of levothyroxine for diet support. Athletes should slowly increased when starting and decreased when ending the cure so the thyroid gland will be adjusted smoothly. The medication usually last 4-6, maximum 8 weeks
However, always remember not to take steroids online or other medications if you are pregnant for the cases of women. The doctor must regularly examine you for this possibility. Tell your doctor all of your health conditions as there may some interactions with your current medication of steroids online. Importantly, they should extra supervise you in case you have an existing condition. Lastly, only the doctor or a nurse can administer these steroids online. Your dose depends on your condition and your doctor will decide the dosage.
Browse other Peptides, Ancillaries and check the different types of supplements HERE. |
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