Methandionex 25

$90.00

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ACTIVE HALF-LIFE 6-8 hours
TABLET COUNT: 50 COUNTS
 CLASSIFICATION Anabolic Steroid
 DOSAGE 150-350 mg/week
 ACNE Yes
 WATER RETENTION High
 HBR Yes
 HEPATOTOXICITY Yes
 AROMATIZATION High

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SKU: EURO97813 Categories: , , ,

Description

The active ingredient is Methandienone, an anabolic steroid. When it gets inside the cell’s nucleus, it increases the synthesis of DNA, RNA and structural proteins, activates the chain enzymes of tissue respiration and enhances tissue ATP synthesis respiration and accumulate macroergs inside the cell. It stimulates anabolic processes and inhibits catabolic. Leads to a significant increase in muscle mass, reduces body fat adipose tissue, promotes calcium deposition in the bones, the body retains nitrogen, phosphorus, sulfur, potassium, sodium and water.

Androgenic activity (low) may contribute to the development of secondary sexual characteristics of male type.

Quickly and completely absorbed in the gastrointestinal tract, it has the effect of “first pass” through the liver. At 90% it is associated with specific blood globulins carriers. Duration – up to 14 hours.

The effects of the drug

Rapid increase in muscle mass;
Increases power performance;
Increased appetite;
Low fat burning;
Strengthens the skeletal system.

Possible side effects

gynecomastia (feminization, breast enlargement). To prevent it, during the cycle it is required to apply the anti-estrogens (Arimidex, Proviron, Proviroxyl), which are almost 100% effective. Upon completion of the cycle, it is important to carry out post-cycle therapy, including such drugs as Nolvadex and Clenbuterol.
toxicity. Since Methandienone refers to the 17 alpha methyl group, it gives it the opportunity to not break down in the liver, but having anabolic effect, it has on a moderate toxic effects when inflating the dosage. If you have an intense, long-lasting AS cycle of high-dose, then use hepatoprotective drugs after the cycle, at PCT. During the cycle, the best solution is combining Methandienone with an injectable anabolic (eg, Deca), to relieve the load on the liver (as AS injections are absolutely non-toxic).
water retention. It occurs mainly in the muscles, which gives a greater effect for a visible musculature. After completing the cycle, the water is drained and the weight falls – the so-called rollback phenomenon. This effect can be significantly reduced with the help of anti-estrogens on the cycle and a full and proper conduct of PCT.

Methandienone Cycles

Methandienone cycle for men, whose aim is a set of muscle mass. Usual Methandienone dosage is about 20-40 mg per day. Large dosage does not bring the best results, but rather there are the likelihood of side effects. Most optimal dosage is considered 30 mg per day, divided into three equal reception. At the end of the cycle there is a significant increase in mass and strength. Must be included in the cycle – anti-estrogens (especially Proviron), to improve the efficiency of the cycle, as well as to reduce the likelihood of side effects.

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DescriptionACTIVE HALF-LIFE 6-8 hours TABLET COUNT: 50 COUNTS  CLASSIFICATION Anabolic Steroid  DOSAGE 150-350 mg/week  ACNE Yes  WATER RETENTION High  HBR Yes  HEPATOTOXICITY Yes  AROMATIZATION HighACTIVE INGREDIENT: OXYMETHOLONE 50mg TABLET COUNT: 100 COUNTS ACTIVE HALF-LIFE: 9 HOURS CLASSIFICATION: ANABOLIC STEROID DOSAGE MEN: 50-100 MG/DAY DOSAGE WOMEN: 5-30 MG/DAY ACNE: RARELY WATER RETENTION: NO HBR: NO HEPATOXITY: LOW AROMATIZATION: NO Ship From: EuropeACTIVE INGREDIENT: Exemestane 25 mg TABLET COUNT: 30 COUNTS ACTIVE HALF-LIFE: 9 HOURS CLASSIFICATION: ANABOLIC STEROID DOSAGE MEN: 25-50 MG/DAY DOSAGE WOMEN: 5-30 MG/DAY ACNE: RARELY WATER RETENTION: NO HBR: NO HEPATOXITY: LOW Ship From: EuropeActive: (anastrozole) Tabs Molar mass: 293.366 g/mol CAS ID: 120511-73-1 Formula: C17H19N5 Elimination half-life: 46.8 hours Trade name: Arimidex, others Metabolism: Liver (85%)Active Ingredient: Exemestane 25 Mg Tablet Count: 25 Counts Active Half-life: 9 Hours Classification: Anabolic Steroid Dosage Men: 25-50 Mg/day Dosage Women: 5-30 Mg/day Acne: Rarely Water Retention: No Hbr: No Hepatoxity: LowActive Ingredient: Stanozolol 10mg Tablet Count: 50 Tablets Active Half-life: 9 Hours Classification: Anabolic Steroid Dosage Men: 20-50 Mg/day Acne: Yes Water Retention: No Hbr: Perhaps Hepatoxity: Yes
ContentThe active ingredient is Methandienone, an anabolic steroid. When it gets inside the cell’s nucleus, it increases the synthesis of DNA, RNA and structural proteins, activates the chain enzymes of tissue respiration and enhances tissue ATP synthesis respiration and accumulate macroergs inside the cell. It stimulates anabolic processes and inhibits catabolic. Leads to a significant increase in muscle mass, reduces body fat adipose tissue, promotes calcium deposition in the bones, the body retains nitrogen, phosphorus, sulfur, potassium, sodium and water. Androgenic activity (low) may contribute to the development of secondary sexual characteristics of male type. Quickly and completely absorbed in the gastrointestinal tract, it has the effect of “first pass” through the liver. At 90% it is associated with specific blood globulins carriers. Duration – up to 14 hours. The effects of the drug Rapid increase in muscle mass; Increases power performance; Increased appetite; Low fat burning; Strengthens the skeletal system. Possible side effects gynecomastia (feminization, breast enlargement). To prevent it, during the cycle it is required to apply the anti-estrogens (Arimidex, Proviron, Proviroxyl), which are almost 100% effective. Upon completion of the cycle, it is important to carry out post-cycle therapy, including such drugs as Nolvadex and Clenbuterol. toxicity. Since Methandienone refers to the 17 alpha methyl group, it gives it the opportunity to not break down in the liver, but having anabolic effect, it has on a moderate toxic effects when inflating the dosage. If you have an intense, long-lasting AS cycle of high-dose, then use hepatoprotective drugs after the cycle, at PCT. During the cycle, the best solution is combining Methandienone with an injectable anabolic (eg, Deca), to relieve the load on the liver (as AS injections are absolutely non-toxic). water retention. It occurs mainly in the muscles, which gives a greater effect for a visible musculature. After completing the cycle, the water is drained and the weight falls – the so-called rollback phenomenon. This effect can be significantly reduced with the help of anti-estrogens on the cycle and a full and proper conduct of PCT. Methandienone Cycles Methandienone cycle for men, whose aim is a set of muscle mass. Usual Methandienone dosage is about 20-40 mg per day. Large dosage does not bring the best results, but rather there are the likelihood of side effects. Most optimal dosage is considered 30 mg per day, divided into three equal reception. At the end of the cycle there is a significant increase in mass and strength. Must be included in the cycle – anti-estrogens (especially Proviron), to improve the efficiency of the cycle, as well as to reduce the likelihood of side effects.Oxymetholone 50mg x 100 tablets Oxymetholone is a powerful steroid that produces very noticeable weight gains in a very short time. Unfortunately, it is also highly toxic in the liver and produces some very unfavorable side effects, such as headaches, and bloating. The gains are very dramatic.Exemestane is a synthetic androgen analogue. It’s is a steroidal inhibitor of aromatase which  binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Exemestane has been associated with a low rate of serum enzyme elevations during therapy and rare instances of clinically apparent liver injury. This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Exemestane is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Exemestane decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers. Exemestane is usually not used in women of childbearing age. Exemestane is usually taken once a day after a meal. Take Exemestane at around the same time every day. You may need to take Exemestane for several years or longer. Continue to take Exemestane even if you feel well. Do not stop taking Exemestane without talking to your doctor. Effect On Estrogens Plasma estrogen (estradiol, estrone, and estrone sulfate) suppression is seen starting at a 5-mg daily dose of Exemestane, with a maximum suppression of at least 85% to 95% achieved at a 25-mg dose. Exemestane 25 mg daily reduces whole body aromatization (as measured by injecting radiolabeled androstenedione) by 98% in postmenopausal women with breast cancer. After a single dose of Exemestane 25 mg, the maximal suppression of circulating estrogens occurres 2 to 3 days after dosing and persisted for 4 to 5 days. Effect On Corticosteroids In multiple-dose trials of doses up to 200 mg daily, Exemestane selectivity was assessed by examining its effect on adrenal steroids. Exemestane did not affect cortisol or aldosterone secretion at baseline or in response to ACTH at any dose. Thus, no glucocorticoid or mineralocorticoid replacement therapy is necessary with Exemestane treatment. Other Endocrine Effects Exemestane does not bind significantly to steroidal receptors, except for a slight affinity for the androgen receptor (0.28% relative to dihydrotestosterone). The binding affinity of its 17dihydrometabolite for the androgen receptor, however, is 100 times that of the parent compound. Daily doses of Exemestane up to 25 mg had no significant effect on circulating levels of androstenedione, dehydroepiandrosterone sulfate, or 17-hydroxyprogesterone, and were associated with small decreases in circulating levels of testosterone. Increases in testosterone and androstenedione levels have been observed at daily doses of 200 mg or more. A dose-dependent decrease in sex hormone binding globulin (SHBG) has been observed with daily Exemestane doses of 2.5 mg or higher. Slight, nondose-dependent increases in serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels have been observed even at low doses as a consequence of feedback at the pituitary level. Exemestane 25 mg daily had no significant effect on thyroid function [free triiodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH). Absorption Exemestane is distributed extensively into tissues. Exemestane is 90% bound to plasma proteins and the fraction bound is independent of the total concentration. Albumin and α11-acid glycoprotein both contribute to the binding. The distribution of Exemestane and its metabolites into blood cells is negligible. Metabolism Exemestane is extensively metabolized. The initial steps in the metabolism of Exemestane are oxidation of the methylene group in position 6 and reduction of the 17-keto group with subsequent formation of many secondary metabolites. Each metabolite accounts only for a limited amount of drug-related material. The metabolites are inactive or inhibit aromatase with decreased potency compared with the parent drug. One metabolite may have androgenic activity [see Pharmacodynamics]. Studies using human liver preparations indicate that cytochrome P 450 3A4 (CYP 3A4) is the principal isoenzyme involved in the oxidation of Exemestane. Exemestane is metabolized also by aldoketoreductases.
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