| Content | TB-500 is a synthetic peptide version of the naturally occuring healing protein present in about all human and mammalian cells known as Thymosin Beta 4 (TB4). Research has shown TB 500 to have beneficial effects on wound healing, injury recovery, flexibility, and inflammation. These desirable effects are accomplished through TB 500’s influence on blood cell and blood vessel development, cellular differentiation, and cell migration. A major part of its healing capability stems from the peptide’s regulation of actin, a cell building protein essential to healing and wound repair.
TB-500 Dosage
TB500 comes as a freeze dried (lyophilized) powder. Research has shown that best results are achieved when bacteriostatic sodium chloride 0.9% is used to reconstitute thymosin peptides. TB 500 dosages can range from 5mg to 20 mg per week. Administration is generally divided into 2-3 injections per week. Once the peptide is built up in the system, the weekly dosage is generally lowered a bit to a maintenance dosage of about half or less of the original weekly dose. Administration of maintenance dosage can be made once per week.
TB500 is typically injected subcutaneously, though it can also be injected into muscle if desired.
How to Store TB 500: Store the product at room temperature in a non-humid environment. The vial should be shielded from light. An opened vial can be kept for up to 8 days refrigerated.
What is TB-500
TB 500 research illustrates multiple properties that have provided the impetus for a worldwide series of clinical trials of potential effectiveness for thymosin beta-4 in promoting repair of wounds in skin, cornea and heart. Thymosin beta 4 is produced in the thymus gland and is found in high concentrations in wound fluids. As such it has been observed to facilitate healing of injured tissue in the body.
TB-500 is a naturally occurring peptide found in high concentrations in blood platelets, wound fluid and other tissues. TB-500 peptides for research are not growth factors; rather major actin regulating protein peptides. TB 500 has been found to play an important role in protection, regeneration and remodeling of injured and/or damaged tissues. The gene for Thymosin Beta-4 has also been found to be one of the first to be stimulated after an incident of injury.
Present in almost all human and animal cells, Thymosin Beta 4 is naturally occurring wound healing peptide. TB 500 is a synthetically made version of TB4 that facilitates healing and recovery by helping build new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration. For the overworked or injured individual, TB 500 offers extremely enticing wound healing effects.
How Does TB 500 Work?
TB 500 is able to help recovery by exerting effects on actin. By up-regulating this cellular protein, TB 500 is able to capitalize on actin’s positive effects. These include the promotion of cell migration and proliferation. As a result, new blood vessels form and inflammation can be regulated so that healing and recovery are optimized. In addition, TB 500’s unique molecular structure allows it to travel long distances in the body. This enables it to exert a “systemic” effect, seeking out and helping those areas of the body suffering injury. Further beneficial results of TB 500 administration can include reduced inflammation and enhanced flexibility. There have even been some reports of regrowing and darkening of hair.
What TB 500 Side Effects Are There?
There are many positive effects associated with Tb500 use, including enhanced recovery, reduced inflammation, and improved flexibility. The peptide works very effectively to aid recovery of slow healing injuries such as those to connective tissue, i.e. tendons and ligaments. Muscle injuries and injuries to skin are greatly helped as well. From reports from users and researchers around the globe, TB 500 seems to cause very few, if any, serious negative side effects.
Most peptides generally can produce a lightheadedness or nauseous feeling upon injection. Also, flu-like symptoms are prevalent among many other peptides as well. However, the incidence of these negative side effects occurring with TB500 administration is reported to be very low, if at all. TB 500 appears to be a very well tolerated peptide among users.
The information presented on this web site is not intended to take the place of your personal physician’s advice and is not intended to diagnose, treat, cure or prevent any disease. | Oxytocin is a hormone secreted by the posterior lobe of the pituitary gland, a pea-sized structure at the base of the brain.
It's sometimes known as the "cuddle hormone" or the "love hormone," because it is released when people snuggle up or bond socially. Even playing with your dog can cause an oxytocin surge, according to a 2009 study published in the journal Hormones and Behavior. But these monikers may be misleading.
Oxytocin can also intensify memories of bonding gone bad, such as in cases where men have poor relationships with their mothers. It can also make people less accepting of people they see as outsiders. In other words, whether oxytocin makes you feel cuddly or suspicious of others depends on the environment.
Oxytocin in women
Oxytocin is a particularly important hormone for women. "Oxytocin is a peptide produced in the brain that was first recognized for its role in the birth process, and also in nursing," said Larry Young, a behavioral neuroscientist at Emory University in Atlanta, Georgia.
The hormone causes uterine contractions during labor and helps shrink the uterus after delivery. When an infant suckles at his or her mother's breast, the stimulation causes a release of oxytocin, which, in turn, orders the body to "let down" milk for the baby to drink.
Oxytocin also promotes mother-child bonding. Studies show that "female rats find pups to be aversive if [the females are] virgins," Young told Live Science. "But once they give birth, the brain is transformed, so they find the pups irresistible," he said. And similar findings are seen in humans.
A 2007 study published in the journal Psychological Science found that the higher a mom's oxytocin levels in the first trimester of pregnancy, the more likely she was to engage in bonding behaviors such as singing to or bathing her baby. [11 Interesting Effects of Oxytocin]
Although maternal bonding may not always be hardwired — after all, human females can adopt babies and take care of them — oxytocin released during pregnancy "does seem to have a role in motivation and feelings of connectedness to a baby," Young said. Studies also show that interacting with a baby causes the infant's own oxytocin levels to increase, he added.
Oxytocin in men
In men, as in women, oxytocin facilitates bonding. Dads who got a boost of oxytocin via a nasal spray played more closely with their 5-month-old babies than dads who didn't get the hormone zap, a 2012 study found. (There is another hormone, called vasopressin, which plays a stronger role in men.)
This anti-social effect of a social hormone brings some nuance to the story of oxytocin. In one study, researchers found that Dutch students given a snort of the hormone became more positive about fictional Dutch characters, but were more negative about characters with Arab or German names. The finding suggests that oxytocin's social bonding effects are targeted at whomever a person perceives as part of their in-group, the researchers reported in January 2011 in the journal PNAS.
In another study, published in PNAS in 2010, men were given a dose of oxytocin and asked to write about their mothers. Those with secure relationships described their moms as more caring after the hormone dose. Those with troubled relationships actually saw their mothers as less caring. The hormone may help with the formation of social memories, according to the study researchers, so a whiff strengthens previous associations, whether good or bad.
"My view of what oxytocin is doing in the brain is making social information more salient," Young said. "It connects brain areas involved in processing social information — whether it's sights, faces, sounds or smells — and helps link those areas to the brain's reward system."
Oxytocin sprays and side effects
Oxytocin nose sprays also have been considered for use in treating autism. The neurological disorder is marked by struggles with social functioning, so a small 2013 study published in the journal PNAS gave a dose to children and teens with autism and asked the participants to identify emotions based on pictures of people's eyes.
The participants weren't any better at identifying the emotions after the oxytocin burst, but the regions of their brains associated with social interaction became more active. The increased processing could mean that a burst of oxytocin might help cement behavioral therapy for kids with the disorder.
"When you think about using oxytocin to treat diseases like autism, you want to make sure you do it in a context where the social information is positive," Young said.
Use of oxytocin sprays outside of a medical context is far murkier, however. The sprays sold online without a prescription promise stress relief and social ease, but they are not regulated by the Food and Drug Administration (FDA). That means that nothing is known about their efficacy, side effects, or even whether they contain any oxytocin.
There are no long-term studies on the side effects of the legitimate oxytocin sprays used in hormone research; most studies give people one dose of the hormone only. Pitocin, a synthetic version of oxytocin given intravenously to stimulate labor, has side effects that include nausea, vomiting and stomach pain. | Insulin-like growth factor-1 (IGF-1) helps encourage normal bone and tissue growth and development and also has the ability to decrease blood glucose levels.
IGF-1 advances to fat cells and therefore burns fat. Subsequently, it increases lean body mass and decreases fat. These effects are desired mostly by athletes and bodybuilders. Increased IGF-1 levels are also comparable to weight gain. This weight gain is a result of lean body mass growth, not fat production.
IGF-1 is favored in the bodybuilding industry and for people who workout regularly. It helps enhance recovery time after workout and improves energy during the workout.
IGF-1 injections are common for adults and children if they have a growth hormone deficiency. IGF-1 contains many necessary amino acids that can help children who are not developing at a standard rate and supplement adults that are deficient.
Research has also shown that the anabolic effects of IGF-1 may reflect inhibited protein breakdown and stimulated protein synthesis in skeletal muscle and that this response may be caused by a direct effect of IGF-1 on muscle tissue, therefore assisting burns on the skin and other tissue abnormalities.
Mechanism of Action
IGF-1 is a hormone found naturally in human blood. Its primary function is to manage the effects of growth hormone in the body. Normal IGF-1 and growth hormone functions include tissue and bone growth. IGF-1 is formed in different tissues as a result of growth hormone in the blood.
IGF-1 promotes systemic body growth, and has growth-stimulating effects on mostly every cell in the body, mainly bone, cartilage, skeletal muscle, liver, kidney, nerve, skin and lung cells. As well as the insulin-like effects, IGF-1 can also manage cellular DNA synthesis.
Administration
Mode of Administration: Subcutaneous injection to a fleshy part of the body, typically to the stomach or abdominal area. IGF-1 can also be administered intramuscularly.
Before administering IGF-1, always be sure to use a clean and sterile syringe.
Hold the IGF-1 vial upright and insert the syringe in the center of the cap.
Draw the plunger until you have the correct amount (see ‘Dosage’ below) in the syringe and carefully remove it.
Before administering the syringe, use alcohol to cleanse the area of skin.
Pinch the skin around the area to be injected, leave about 2 cm on each side.
Hold the syringe at a 90 degree angle to your skin and swiftly insert the syringe.
Depress the plunger fully, until the syringe is empty, and carefully draw out.
Dosage
Dosage Amount: For lean muscle growth and fat loss
40 mcg - 50 mcg daily (men)
10 mcg - 20 mcg daily (women)
IGF-1 should not be injected more than twice daily
A typical dosage cycle of IGF-1 will continue for 2 to 12 weeks
Children and adults who are prescribed IGF-1 for development deficiency should consult with a care provider about correct dosing.
Side Effects
The side effects of IGF-1 can be similar to those of other growth hormones. These include growth of excess body tissue, also known as acromegaly, and damage to the joints, liver, and heart. IGF-1 could possibly cause joint pain, muscle pain, headaches and nausea. IGF-1 can also decrease levels of blood glucose, resulting in hypoglycemia. Researchers also associate IGF-1 with an increased risk of developing some cancers, such as lung, breast, colorectal and prostate.
Benefits
Facilitation of protein synthesis in the body
Regulation of stored fat and channeling it to be used for energy production, resulting in fat loss
Promotion of positive effects on metabolism and increasing lean body mass and muscle growth
Protection against autoimmune disease, heart disease and plaque buildup
Aid development in young children and adults deficient in essential amino acids
Improvement in blood sugar regulation
Promotion of optimal health, wellness and fitness in users | BPC 157 2MG is a peptide with 15 amino acids which helps to treat stomach problems back to its original state such us the lining in the stomach and intestines. It is advised to start from small amounts per mg (1mg-10mg). For average use, 2mg will last for 10 days. | Sustanon – is one of the most popular steroids today. It highly appreciated by those who use it. The peak of the popularity of this drug has been by ’80 – ’90 years of the twentieth century and at the same time on its popularity a huge number of articles on the pole position of the drug was written.
Buy Sustanon – which means to buy one of the most advantageous products of our times. Sustanon has the following advantages: it consists of a mixture of four testosterones, which, thanks to a specific structure have a synergistic effect. All testosterone esters, which are part of Sustanon have different absorption rate and this makes it possible to maintain a constant anabolics level in the blood for a month. Use of injectable Sustanon is enough one time in three weeks.
Sustanon Effects and Reviews
Sustanon is used to increase the weight. Among the side effects is distinguished gynecomastia, deterioration of natural testosterone by the body, swelling, as well as deposits of fat on the female type. If you decide to buy Sustanon, keep in mind that it can be used only in male persons who have reached twenty-one years
How to Use Sustanon: Dosage, Cycle, PCT
If you want to achieve the maximum effect from the use of Sustanon, then use it in conjunction with diet and nutrition for a set of muscle mass. This steroid has effects on the body next day and is active for 3-4 weeks. After the cycle, you will notice a strong increase in strength and will gain weight.
The course lasts for 6 weeks. It is done a total of 5 or 6 injections. It is necessary to do them once a week (at a dose of 250-500 mg). From the second week of the cycle, it is desirable to start the use of Nolvadex (10 mg daily) and complete its application – 4 weeks after the last injection.
Warnings: Keep out of reach of children. For adults only. | Melanotan II analog of alpha-melanocyte stimulating hormone (a-MSH). Melanotan peptides are safe and efficacious with growing long term data. Melanotan 2 is a freeze dried peptide sealed in a sterile multi-use vial. Tanning injections of synthetic potent a-MSH allow for development of photo-protective suntans in all skin types.
Melanotan 2 Dosage
Range: 100mcg – 1mg
Melanotan II Side Effects
Melanotan injections act on melanocytes to stimulate melanin production. Melanin is the body’s pigment responsible for a photoprotective safe tan.
Sunless tanning injections begin with the peptide sequence: His-Phe-Arg-Trp. Melanotan peptides Melanotan II binds to melanocortin receptors influencing pigmentation, inflammation, energy, appetite and sexual function. Melanotan 2 has a small protective amino acid structure that effects the melanocortin 1, 3, 4 and 5 receptors.
Melanotan 2 Peptide Hormone
Melanotan 2 is a small efficient molecule as compared to the linear original Melanotan I design after natural melanocyte stimulating hormone peptide. Melanotan is approximately 1,000 times more potent than natural a-MSH. Melanotan half life of minutes, Melanotan 2 half life ~1 hour.
Melanin skin tanning after Melanotan injection
Folks who never tan, always burn in the sun, can achieve a natural tan when using Melanotan II. For people with sun allergies/mutated receptors, synthetic melanotropin peptide supplements offer life changing opportunity. A natural tan developed over time is the best defense against cancer, to which the fair skin can now acheive. Melanotan was designed to reduce cancer rates and potentially become effective as a sunless tanning agent.
Melanotan results
Fitzpatrick skin type: Skin type I and II, the lower of the skin types on the Fitzpatrick scale are the best candidates for Melanotan.
Athletes and fitness enthusiasts use Melanotan for accelerated tanning, libido increase and appetite suppression. Melanotan 2 was dubbed the Barbie drug and has been highlighted in wired magazine. Synthetic melanocortin therapy helps attain a tan with the least amount of exposure to harmful ultraviolet radiation. Melanotan II continues to be the most effective tanning peptide sold online.
Fitzpatrick Skin Type Description
I Extremely fair skin, always burn, never tans.
II Fair skin, always burns, sometimes tans.
III Medium skin, sometimes burns, always tans.
IV Olive skin, rarely burns, always tans.
V Moderately pigmented brown skin, never burns, always tans.
VI Markedly pigmented black skin, never burns, always tans.
Peptide Hormone Therapy: Melanotan stimulates melanin, particularly low fitzpatrick types.
Disclaimer: Please pursue information regarding the usage of these products from your own research, academic journals, or the research of your in-house scientific team. Products sold for research purposes are not for human consumption. Melanotan Peptides are not known to contain filler (mannitol).
review melanotan results chart melanin density after tanning injections
Reconstituted with bacteriostatic water, Melanotan 2 research peptide remains potent and preserved. Reconstituting Melanotan 2 peptide is a necessity and will require proper due diligence for results. Nasal sprays, pre-mixed Melanotan 2, pills, oral melanotan2 are not legitimate. Enzymes will render the peptide inactive if ingested. Purchase only pure Melanotan II custom synthesis.
Melanotan Shipping: Melanotan peptides are durable and stable. Shipping in the summer not a problem for tanning melanocortins. When receiving MT-2 it is recommended to store in the refrigerator. Save money and do not pay for cold melanotan 2 shipments. Further, do not store Melanotan 2 in freezer.
Mixing Melanotan 2: 1-2ml Bacteriostatic water reconstitutes and preserves tanning peptide Melanotan best. Dilute with more volume for improved dosing accuracy (micrograms).
Dosage Calculator: Add 100 units (1ml) of water to the vial. 1ml Bacteriostatic water will minimize injection volume and simplify arithmetic. Dosing measurements are often mentioned in both milligram (mg) and microgram (mcg).
1ml syringe (U100), 1ml Bac Water to Reconstitute
Calculations for .5mg or 500mcg dose:
Step Dosage
Step 1 1ml
Step 2 10mg Melanotan II
Step 3 1ml Bacteriostatic Water
Step 4 500mcg Dose
5 units on your insulin syringe (approximately 1/20th of a U100 syringe).
Needles: 29-31 gauge X 1/2″, 1 CC (100 unit). That is a typical insulin needle used to mix as well as inject. Use needles one time only. Once your technique perfected, injections are almost painless. Smaller 1/2 and 1/3cc syringes offer greater measurement accuracy and pre-loading convenience.
Melanotan Dosage: Your first injection should be a very small dose, for example .25mg (250mcg). See how you react. Goal should be to feel nothing. Dose after dinner, before bed. Any dosing chart stating that you should take a high dose (according to your weight) is dated and potentially dangerous.
Loading dose: Load with .5-1mg once a day. People who have used doses in this range generally report getting excellent results. Don’t worry if you miss occasional days. It will not make much difference, focus on the cumulative effects. A tan generally sets in 3 days after UV rays. Dose and expose yourself gradually to UVR when tanning.
Maintenance dosing: Maintenance is taking doses less frequently than daily to avoid becoming darker than you want. Yes, that will happen. With enough UVR, you will get much darker than you have even been before. A maintenance dose can help prolong super-physiological photo-protection MT-2 delivers.
UV Radiation: Melanotan is a poor sunless tanner. UV (from sun or a tanning bed) light is necessary to develop a tan for most folks. Without it, almost nothing happens. In other words, NO UV = NO TAN. Melanotan use for a full month and with UV exposure, you (and your friends) will be astounded by how fast and how dark MT-II tanning results. Areas of skin that are typically sun-exposed in your day to day life will respond more readily to the effects of the melanotan peptides, take photo therapy serious with Melanotan II.
Melanotan 2 Weight Loss: Melanotan II peptide usage results in adipocyte lipolysis. Dose low-moderate between meals to increase fatty acid oxidation, reduce food intake, and increase energy.
Side-effects of Melanotan II
Possible short-term side effects include: nausea, appetite loss, facial flushing and increased libido. Melanotan side effects may be noticeable during the first few days of treatment but should taper off as the body desensitizes.
Do you have to inject Melanotan Peptides?
Yes. The best, most efficient method of administering Melanotan peptides are subcutaneous (subq) injection. Nasal sprays are inconsistent and inefficient at best. No detectable levels were observed following oral melanotan dosing.
Note: There are many things you will need to consider before experimenting with melanotans peptide. Cyclic analogues (Melanotan II) have a wide range of peripheral effects and systemic control is always going to pose an issue in clinical research. Needless to say, Melanotan2 is not an approved or regulated product. Melanotan is legal to buy, possess, etc.
Subcutaneous injection
When supplementing Melanotan to tan keep in mind that tanning is literally a side effect. The tanning response is, in reality, a physiological repair mechanism to UV damage of the cells (epidermis/dermis). Melanocyte stimulating hormone is not going to color your skin, it is going to make your own cells create its own tan and that in turn creates protection. If you are looking to be some bronzed beach God with perfectly uniform and specific color then you are better off to going to mystic tan. Redheads, for example, naturally produce a variant form of melanin that is yellowish-red (pheomelanin). Do not expect a brown tan on ginger skin without serious diligence.
Melanotan Dosage: Knowing your skin type is one detail which will help create a public user log. There are thousands of melanotan users worldwide who share the experience. Raise awareness and help others who want to hear success stories, complications and failures.
Am I a candidate for Melanotan?
Melanotan is best suited for the folks with skin types I & II. Prior sun damage, scars, tattoos, freckles, moles, hair color, etc are deciding factors prospective MT-2 users consider.
How should I dose Melanotan II?
Melanotan II dosage it is recommended to start out small and build up. A typical starting dose is around .25mg and max dose reaching 1mg. Desensitization happens quick, the first administration is an opportunity to dose low to avoid Melanotan 2 side effects. Same goes for bremelanotide (PT-141) dosage unfortunately.
Melanotan Instruction: There is no magic pill or formula. Instructions do not exist for research peptides. Few dermatologists are familiar with Melanotan. The skin is a large, unpredictable organ. Feel comfortable and confident with MT-II before use. Check out as many before and after photos and user logs as you can. A skin type I individual may have to commit months of dedication before dialing in their desired results, be patient and ask questions.
How much Melanotan peptide should I purchase?
Skin Type Dosage
Skin Type I 30-50mg
Skin Type II 20-30mg
Skin Type III 10mg
Should last entire summer or season.
How soon will I see Melanotan results? Change in tone after 2-3 weeks should be anticipated. If you have freckles, expect them to get darker before your actual skin color changes. Brace yourself, within days Melanotan will.
How long will my tan last? A tan developed using Melanotan 2 lasts much longer than an ordinary tan. A well-tanned person returning from a beach holiday will lose most of the tan in a month if they stop getting sun. But if they had been using Melanotan 2 and continued on maintenance after returning, they would still have most of their tan 3 months later.
The information presented on this web site is not intended to take the place of your personal physician’s advice and is not intended to diagnose, treat, cure or prevent any disease. |
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