| Description | ACTIVE HALF-LIFE?5-6 Hours
?CLASSIFICATION?Anabolic Steroid
?DOSAGE?150-350mg/week
?ACNE?Yes
?WATER RETENTION?High
?HBR?Yes
?HEPATOTOXICITY?Yes
?AROMATIZATION?High | ACTIVE INGREDIENT: Exemestane 25 mg
TABLET COUNT: 30 COUNTS
ACTIVE HALF-LIFE: 9 HOURS
CLASSIFICATION: ANABOLIC STEROID
DOSAGE MEN: 25-50 MG/DAY
DOSAGE WOMEN: 5-30 MG/DAY
ACNE: RARELY
WATER RETENTION: NO
HBR: NO
HEPATOXITY: LOW
Ship From: Europe | Product Name: Halotestin 10mg
Active Ingredient: Fluoxymesterone 10mg
Active Life: 9 Hours
Drug Class: Androgen; Anabolic Steroid
Detection Time: 11 Months
Common Doses: 10-20 mg/day
Blood pressure: Perhaps
Acne: Yes
Water retention: No
Aromatisation: No
Liver toxicity: High
Decrease HPTA function: None | Active Ingredient: Mesterolone 10mg
Bottle Count: 50 Tablets
Active Half-life: 12 Hours
Classification: Anabolic Steroid
Dosage Men: 30-100 mg/day
Acne: Yes
Water Retention: No
Concentration: 10 mg/Pill
Presentation: 50 Tablets (Total box 500 mg)
Dosage: 30-100mg per day over the course of 8-12 weeks | Active Ingredient: Stanozolol 10mg
Tablet Count: 100 tabs
Active Half-life: 9 Hours
Classification: Anabolic Steroid
Dosage Men: 20-50 Mg/day
Acne: Yes
Water Retention: No
Hbr: perhaps
Hepatoxicity: yes
Aromatization: No
Ship From: USA | Active Ingredient: Chlorodelydromethytestosterone 10mg
Tablet Count: 50 Counts
Active Half-life: 9 Hours
Classification: Anabolic Steroids
Dosage Men: 10mg /day
Dosage Women: 10mg/day
Acne: Rarely
Water Retention: No
Hbr: No
Hepatoxity: Low
Aromatization: Yes |
| Content | [vc_row][vc_column][vc_column_text]The active ingredient is Methandienone, an anabolic steroid. When it gets inside the cell?s nucleus, it increases the synthesis of DNA, RNA and structural proteins, activates the chain enzymes of tissue respiration and enhances tissue ATP synthesis respiration and accumulate macroergs inside the cell. It stimulates anabolic processes and inhibits catabolic. Leads to a significant increase in muscle mass, reduces body fat adipose tissue, promotes calcium deposition in the bones, the body retains nitrogen, phosphorus, sulfur, potassium, sodium and water.
Androgenic activity (low) may contribute to the development of secondary sexual characteristics of male type.
Quickly and completely absorbed in the gastrointestinal tract, it has the effect of ?first pass? through the liver. At 90% it is associated with specific blood globulins carriers. Duration ? up to 14 hours.
The effects of the drug
Rapid increase in muscle mass;
Increases power performance;
Increased appetite;
Low fat burning;
Strengthens the skeletal system.
Possible side effects
gynecomastia (feminization, breast enlargement). To prevent it, during the cycle it is required to apply the anti-estrogens (Arimidex, Proviron, Proviroxyl), which are almost 100% effective. Upon completion of the cycle, it is important to carry out post-cycle therapy, including such drugs as Nolvadex and Clenbuterol.
toxicity. Since Methandienone refers to the 17 alpha methyl group, it gives it the opportunity to not break down in the liver, but having anabolic effect, it has on a moderate toxic effects when inflating the dosage. If you have an intense, long-lasting AS cycle of high-dose, then use hepatoprotective drugs after the cycle, at PCT. During the cycle, the best solution is combining Ultima-Dbol with an injectable anabolic (eg, Deca), to relieve the load on the liver (as AS injections are absolutely non-toxic).
water retention. It occurs mainly in the muscles, which gives a greater effect for a visible musculature. After completing the cycle, the water is drained and the weight falls ? the so-called rollback phenomenon. This effect can be significantly reduced with the help of anti-estrogens on the cycle and a full and proper conduct of PCT.
Ultima-Dbol Cycles
Ultima-Dbol cycle for men, whose aim is a set of muscle mass. Usual Ultima-Dbol dosage is about 20-40 mg per day. Large dosage does not bring the best results, but rather there are the likelihood of side effects. Most optimal dosage is considered 30 mg per day, divided into three equal reception. At the end of the cycle there is a significant increase in mass and strength. Must be included in the cycle ? anti-estrogens (especially Proviron), to improve the efficiency of the cycle, as well as to reduce the likelihood of side effects.[/vc_column_text][/vc_column][/vc_row] | Exemestane is a synthetic androgen analogue. It’s is a steroidal inhibitor of aromatase which binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens.
Exemestane has been associated with a low rate of serum enzyme elevations during therapy and rare instances of clinically apparent liver injury.
This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Exemestane is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Exemestane decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers. Exemestane is usually not used in women of childbearing age.
Exemestane is usually taken once a day after a meal. Take Exemestane at around the same time every day. You may need to take Exemestane for several years or longer. Continue to take Exemestane even if you feel well. Do not stop taking Exemestane without talking to your doctor.
Effect On Estrogens
Plasma estrogen (estradiol, estrone, and estrone sulfate) suppression is seen starting at a 5-mg daily dose of Exemestane, with a maximum suppression of at least 85% to 95% achieved at a 25-mg dose. Exemestane 25 mg daily reduces whole body aromatization (as measured by injecting radiolabeled androstenedione) by 98% in postmenopausal women with breast cancer. After a single dose of Exemestane 25 mg, the maximal suppression of circulating estrogens occurres 2 to 3 days after dosing and persisted for 4 to 5 days.
Effect On Corticosteroids
In multiple-dose trials of doses up to 200 mg daily, Exemestane selectivity was assessed by examining its effect on adrenal steroids. Exemestane did not affect cortisol or aldosterone secretion at baseline or in response to ACTH at any dose. Thus, no glucocorticoid or mineralocorticoid replacement therapy is necessary with Exemestane treatment.
Other Endocrine Effects
Exemestane does not bind significantly to steroidal receptors, except for a slight affinity for the androgen receptor (0.28% relative to dihydrotestosterone). The binding affinity of its 17dihydrometabolite for the androgen receptor, however, is 100 times that of the parent compound.
Daily doses of Exemestane up to 25 mg had no significant effect on circulating levels of androstenedione, dehydroepiandrosterone sulfate, or 17-hydroxyprogesterone, and were associated with small decreases in circulating levels of testosterone.
Increases in testosterone and androstenedione levels have been observed at daily doses of 200 mg or more. A dose-dependent decrease in sex hormone binding globulin (SHBG) has been observed with daily Exemestane doses of 2.5 mg or higher.
Slight, nondose-dependent increases in serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels have been observed even at low doses as a consequence of feedback at the pituitary level. Exemestane 25 mg daily had no significant effect on thyroid function [free triiodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH).
Absorption
Exemestane is distributed extensively into tissues. Exemestane is 90% bound to plasma proteins and the fraction bound is independent of the total concentration. Albumin and α11-acid glycoprotein both contribute to the binding. The distribution of Exemestane and its metabolites into blood cells is negligible.
Metabolism
Exemestane is extensively metabolized. The initial steps in the metabolism of Exemestane are oxidation of the methylene group in position 6 and reduction of the 17-keto group with subsequent formation of many secondary metabolites.
Each metabolite accounts only for a limited amount of drug-related material. The metabolites are inactive or inhibit aromatase with decreased potency compared with the parent drug. One metabolite may have androgenic activity [see Pharmacodynamics]. Studies using human liver preparations indicate that cytochrome P 450 3A4 (CYP 3A4) is the principal isoenzyme involved in the oxidation of Exemestane. Exemestane is metabolized also by aldoketoreductases. | Fluoxymesterone 10mg x 100 tablets
Fluoxymesterone has established itself as a high-quality drug with a high androgenic index. Fluoxy mesteronegives a great increase in strength. Suitable for preparation for competitions, when an athlete needs strength without a large set of muscle mass. In this case, the musculature gets the necessary hardness. | | Stanozolol 10mg x 100 tablets
Stanzolol is a derivative of dihydrotestosterone, although its activity is much milder than this androgen in nature. It is technically classified as an anabolic steroid, shown to exhibit a slightly greater tendency for muscle growth than androgenic activity in early studies. | |
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