Ultima-Selank 5mg

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ACTIVE HALF-LIFE
 CLASSIFICATION
 DOSAGE
 ACNE
 WATER RETENTION
 HBR
 HEPATOTOXICITY
 AROMATIZATION

SKU: BELIGAS-AAS-5635 Categories: , ,

Description

Products are shipping without brand label for security reasons.
The recent boom in biotechnology has opened the door for studying new biologically-active compounds, including “cognitive enhancers” or “nootropics.”

One such compound is Selank — previously known as “TP-7” — which belongs to a class of molecules called synthetic peptides, or small artificially-designed proteins.

Selank has been touted as an “anti-anxiety” compound, and has also been claimed to improve learning and increase energy — supposedly without side-effects or the risk of addiction.

Selank is small and only a fraction of the size of most naturally-occurring proteins. It was developed at the Institute of Molecular Genetics (Russian Academy of Sciences) in cooperation with the V.V. Zakusov Research Institute of Pharmacology (Russian Academy of Medical Sciences), along with its “cousin” drug, Semax.

Selank was derived by combining the sequence of a peptide called tuftsin with another sequence that improves its molecular stability. Tuftsin is naturally-occurring, and makes up one part of the natural antibody IgG.

Both tuftsin and Selank have been reported to reduce anxiety and increased serotonin levels in rats, with Selank being slightly more effective.

Selank has been approved in Russia for the treatment of generalized anxiety disorder (GAD) and for its use as a nootropic. However, the FDA has not approved its use for any conditions. Nonetheless, Selank continues to be available in several countries, where it is often sold as a “nutritional supplement.”

Selank Mechanism of Action

Although the mechanisms behind Selank are not yet fully known for certain, Selank is believed to act in part by stabilizing enkephalins in the blood. Enkephalins are natural peptides in the body that are believed to counteract the stress response.

However, one animal study in mice did not demonstrate the stabilization of enkephalins following dosing with Selank, and the treated mice also did not appear to benefit from any significant “anti-anxiety” effects.

According to some cell studies, Selank may bind to GABA receptors. By extensions, most compounds that bind to GABA receptors generally cause “sedative” effects. In one study of mice treated with Selank, researchers reported increased activity in inhibitory neurons, which rely on GABA. This resulted in less overall brain activity, which is generally consistent with a sedative effect.

In addition, some researchers have reported an increase in BDNF, an important brain-growth compound (neurotropic factor) which has been implicated in learning and memory. Some researchers have suggested that this mechanism may be responsible for some of Selank’s claimed cognitive effects.

Selank has also been reported to influence the levels of the neurotransmitters norepinephrine, dopamine, and serotonin in mice. These neurotransmitters are widely believed to be involved in motivation, focus, and pleasure.

However, according to one animal study in mice, Selank was reported to increase norepinephrine, but reportedly decreased dopamine and serotonin levels. In contrast, in some other treated mice, Selank was reported to increase norepinephrine and dopamine levels, and did not change serotonin. Therefore, its exact effects and mechanisms remain unclear.

Possibly Effective for:

Anxiety

According to one preliminary clinical trial on 62 people, those given Selank reported fewer anxiety symptoms, with a greater decrease being observed in those suffering from pre-existing anxiety disorders.

In another trial, similar benefits were reported in 60 patients suffering from anxiety and phobias, with these effects lasting up to a week after the final dose.

Additionally, in one study of 70 anxiety patients, Selank was reported to increase the effects of phenazepam (an anti-anxiety drug banned in some U.S. states for its recreational use), while also reportedly reducing its rates of negative side-effects (such as drowsiness and memory loss).

In one animal study, Selank was reported to reduce anxiety in mice. The more anxious the mice were to begin with, the more significant the observed changes in their behavior after treatment.

Additionally, Selank was reported to show “anti-anxiety” effects in one study of rats who received 4 weeks of daily treatment.

Although limited, some of the above evidence suggests that Selank may potentially help curb anxiety, although much more research will still be needed to confirm its effectiveness and safety in human users. If you suffer from anxiety, you could have a discussion with your doctor about whether taking Selank might help you — however, always remember that you should never take this supplement in place of what your doctor recommends or prescribes.

Memory

Selank was reported to stabilize memory traces (i.e. potentially improve memory storage) in rats during one 30-day trial. However, it is unclear how these measurements were performed, as memory traces are not detectable as discrete locations in the brain.

One other animal study has reported that Selank may also preserve memory in monkeys.

However, appropriate human studies are lacking, and remains unknown what effects — if any — Selank might have in healthy human users. It is also unclear whether or not this compound would be safe for such users to take (either in the short- or long-term), and so caution would be advised until much more additional research is performed.

Brain Damage Recovery

In one study, researchers gave Selank supplements to rats with toxin-induced brain damage. This drug reportedly restored their brain activity to normal levels.

Depression

Selank has been reported to decrease depression symptoms (immobility during a forced swimming test) in mice. Curiously, it was reported to be more effective at relatively lower rather than higher doses.

Antioxidant Activity in the Liver

In one preliminary animal study, injection of Selank was reported to increase the levels of antioxidants in the livers of stressed mice.

Blood Flow

In one animal study of sedated cats, Selank was reported to decrease blood pressure by about 30% for up to 3 minutes.

It also increased blood flow to the cats’ brain by about 24% for up to 10 minutes [30].

While these preliminary findings are interesting in that they suggest that Selank may have some short-term cardiovascular effects on blood flow, the relatively short durations of these effects is hard to interpret, and may suggest that these effects are not strong or medically significant.

Additionally, these were only observed in animals, and so whether these effects would be similar in healthy human users remains unclear.

Alcohol Withdrawal

Anxiety is one of the more common symptoms involved in alcohol withdrawal. To mimic high alcohol intake, rats were given a 10% solution of ethanol (alcohol) as their sole drinking source for 24 weeks. Selank reportedly decreased the anxiety of these rats after a 48-hour alcohol withdrawal period.

Preventing Weight Gain and Reducing Cholesterol

According to one animal study, rats who were fed a high-fat diet reportedly showed 35% less weight gain when treated with Selank. Additionally, total cholesterol levels for these rats were reportedly reduced by over 58%, and blood glucose levels were reduced by 23.5%.

Cancer

In one animal study, mice with breast cancer were treated with daily doses of Selank and had slower tumor growth. Also, these mice reportedly lived longer than their untreated counterparts.

However, this preliminary finding doesn’t mean that Selank has any value in anticancer therapy. Much more research would be needed to verify and extend these early findings into legitimate medical treatments for cancer. Do not under any circumstances attempt to replace conventional cancer therapies with Selank (or any other supplements)!

Inflammation in the Spleen

After treatment with Selank, the spleens of mice were reported to show increased levels of several inflammatory response genes, which may suggest some degree of protection against the harmful effects of inflammation.

Ulcers

Selank has been reported to reduce the size (area) of stomach ulcers in animal models.

Some researchers have speculated that this may be because this drug increases the flow of lymph — an important component of the immune system — to the stomach.

Nonetheless, much more research in humans would be needed to confirm this effect, as well as its potential mechanisms.

Immune Function

Selank reportedly increased IL-6 in blood cells collected from patients suffering from depression. IL-6 is an inflammatory protein that is believed to help fight off infections.

Additionally, according to one cell-based study, Selank was reported to stimulate the release of interferons, which are anti-viral molecules.

Selank has also been proposed to potentially protect cells against some viral infections. However, one animal study in mice infected with a virus did not report any anti-viral benefits from Selank treatment, which casts doubt on this potential use.

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DescriptionACTIVE HALF-LIFE  CLASSIFICATION  DOSAGE  ACNE  WATER RETENTION  HBR  HEPATOTOXICITY  AROMATIZATIONACTIVE HALF-LIFE 12-36 hours  CLASSIFICATION Peptide Hormone  DOSAGE  ACNE No  WATER RETENTION No  HBR No  HEPATOTOXICITY No  AROMATIZATION NoACTIVE HALF-LIFE  CLASSIFICATION Peptide Hormone  DOSAGE  ACNE No  WATER RETENTION No  HBR No  HEPATOTOXICITY No  AROMATIZATION NoACTIVE HALF-LIFE 7-8 Days  CLASSIFICATION Anabolic Steroid  DOSAGE Men 300-1500 mg/week  ACNE Yes  WATER RETENTION Yes  HBR Perhaps  HEPATOTOXICITY No  AROMATIZATION YesACTIVE HALF-LIFE  CLASSIFICATION Peptide Hormone  DOSAGE  ACNE No  WATER RETENTION No  HBR No  HEPATOTOXICITY No  AROMATIZATION NoACTIVE HALF-LIFE Several Minutes  CLASSIFICATION Peptide Hormone  DOSAGE 500 mcg/day  ACNE No  WATER RETENTION No  HBR No  HEPATOTOXICITY No  AROMATIZATION No
ContentProducts are shipping without brand label for security reasons. The recent boom in biotechnology has opened the door for studying new biologically-active compounds, including “cognitive enhancers” or “nootropics.” One such compound is Selank — previously known as “TP-7” — which belongs to a class of molecules called synthetic peptides, or small artificially-designed proteins. Selank has been touted as an “anti-anxiety” compound, and has also been claimed to improve learning and increase energy — supposedly without side-effects or the risk of addiction. Selank is small and only a fraction of the size of most naturally-occurring proteins. It was developed at the Institute of Molecular Genetics (Russian Academy of Sciences) in cooperation with the V.V. Zakusov Research Institute of Pharmacology (Russian Academy of Medical Sciences), along with its “cousin” drug, Semax. Selank was derived by combining the sequence of a peptide called tuftsin with another sequence that improves its molecular stability. Tuftsin is naturally-occurring, and makes up one part of the natural antibody IgG. Both tuftsin and Selank have been reported to reduce anxiety and increased serotonin levels in rats, with Selank being slightly more effective. Selank has been approved in Russia for the treatment of generalized anxiety disorder (GAD) and for its use as a nootropic. However, the FDA has not approved its use for any conditions. Nonetheless, Selank continues to be available in several countries, where it is often sold as a “nutritional supplement.” Selank Mechanism of Action Although the mechanisms behind Selank are not yet fully known for certain, Selank is believed to act in part by stabilizing enkephalins in the blood. Enkephalins are natural peptides in the body that are believed to counteract the stress response. However, one animal study in mice did not demonstrate the stabilization of enkephalins following dosing with Selank, and the treated mice also did not appear to benefit from any significant “anti-anxiety” effects. According to some cell studies, Selank may bind to GABA receptors. By extensions, most compounds that bind to GABA receptors generally cause “sedative” effects. In one study of mice treated with Selank, researchers reported increased activity in inhibitory neurons, which rely on GABA. This resulted in less overall brain activity, which is generally consistent with a sedative effect. In addition, some researchers have reported an increase in BDNF, an important brain-growth compound (neurotropic factor) which has been implicated in learning and memory. Some researchers have suggested that this mechanism may be responsible for some of Selank’s claimed cognitive effects. Selank has also been reported to influence the levels of the neurotransmitters norepinephrine, dopamine, and serotonin in mice. These neurotransmitters are widely believed to be involved in motivation, focus, and pleasure. However, according to one animal study in mice, Selank was reported to increase norepinephrine, but reportedly decreased dopamine and serotonin levels. In contrast, in some other treated mice, Selank was reported to increase norepinephrine and dopamine levels, and did not change serotonin. Therefore, its exact effects and mechanisms remain unclear. Possibly Effective for: Anxiety According to one preliminary clinical trial on 62 people, those given Selank reported fewer anxiety symptoms, with a greater decrease being observed in those suffering from pre-existing anxiety disorders. In another trial, similar benefits were reported in 60 patients suffering from anxiety and phobias, with these effects lasting up to a week after the final dose. Additionally, in one study of 70 anxiety patients, Selank was reported to increase the effects of phenazepam (an anti-anxiety drug banned in some U.S. states for its recreational use), while also reportedly reducing its rates of negative side-effects (such as drowsiness and memory loss). In one animal study, Selank was reported to reduce anxiety in mice. The more anxious the mice were to begin with, the more significant the observed changes in their behavior after treatment. Additionally, Selank was reported to show “anti-anxiety” effects in one study of rats who received 4 weeks of daily treatment. Although limited, some of the above evidence suggests that Selank may potentially help curb anxiety, although much more research will still be needed to confirm its effectiveness and safety in human users. If you suffer from anxiety, you could have a discussion with your doctor about whether taking Selank might help you — however, always remember that you should never take this supplement in place of what your doctor recommends or prescribes. Memory Selank was reported to stabilize memory traces (i.e. potentially improve memory storage) in rats during one 30-day trial. However, it is unclear how these measurements were performed, as memory traces are not detectable as discrete locations in the brain. One other animal study has reported that Selank may also preserve memory in monkeys. However, appropriate human studies are lacking, and remains unknown what effects — if any — Selank might have in healthy human users. It is also unclear whether or not this compound would be safe for such users to take (either in the short- or long-term), and so caution would be advised until much more additional research is performed. Brain Damage Recovery In one study, researchers gave Selank supplements to rats with toxin-induced brain damage. This drug reportedly restored their brain activity to normal levels. Depression Selank has been reported to decrease depression symptoms (immobility during a forced swimming test) in mice. Curiously, it was reported to be more effective at relatively lower rather than higher doses. Antioxidant Activity in the Liver In one preliminary animal study, injection of Selank was reported to increase the levels of antioxidants in the livers of stressed mice. Blood Flow In one animal study of sedated cats, Selank was reported to decrease blood pressure by about 30% for up to 3 minutes. It also increased blood flow to the cats’ brain by about 24% for up to 10 minutes [30]. While these preliminary findings are interesting in that they suggest that Selank may have some short-term cardiovascular effects on blood flow, the relatively short durations of these effects is hard to interpret, and may suggest that these effects are not strong or medically significant. Additionally, these were only observed in animals, and so whether these effects would be similar in healthy human users remains unclear. Alcohol Withdrawal Anxiety is one of the more common symptoms involved in alcohol withdrawal. To mimic high alcohol intake, rats were given a 10% solution of ethanol (alcohol) as their sole drinking source for 24 weeks. Selank reportedly decreased the anxiety of these rats after a 48-hour alcohol withdrawal period. Preventing Weight Gain and Reducing Cholesterol According to one animal study, rats who were fed a high-fat diet reportedly showed 35% less weight gain when treated with Selank. Additionally, total cholesterol levels for these rats were reportedly reduced by over 58%, and blood glucose levels were reduced by 23.5%. Cancer In one animal study, mice with breast cancer were treated with daily doses of Selank and had slower tumor growth. Also, these mice reportedly lived longer than their untreated counterparts. However, this preliminary finding doesn’t mean that Selank has any value in anticancer therapy. Much more research would be needed to verify and extend these early findings into legitimate medical treatments for cancer. Do not under any circumstances attempt to replace conventional cancer therapies with Selank (or any other supplements)! Inflammation in the Spleen After treatment with Selank, the spleens of mice were reported to show increased levels of several inflammatory response genes, which may suggest some degree of protection against the harmful effects of inflammation. Ulcers Selank has been reported to reduce the size (area) of stomach ulcers in animal models. Some researchers have speculated that this may be because this drug increases the flow of lymph — an important component of the immune system — to the stomach. Nonetheless, much more research in humans would be needed to confirm this effect, as well as its potential mechanisms. Immune Function Selank reportedly increased IL-6 in blood cells collected from patients suffering from depression. IL-6 is an inflammatory protein that is believed to help fight off infections. Additionally, according to one cell-based study, Selank was reported to stimulate the release of interferons, which are anti-viral molecules. Selank has also been proposed to potentially protect cells against some viral infections. However, one animal study in mice infected with a virus did not report any anti-viral benefits from Selank treatment, which casts doubt on this potential use.Euro-HMG 75IU Injection or hMG for short is used to treat infertility in women. It is also known by the name of Menotropin. It is a hormonally active drug that stimulates the production of eggs in the ovaries in cases of women who suffer from ovarian failure. Euro-HMG 75IU Injection is extricated from the urine of postmenopausal females. The urine of a postmenopausal woman contains high levels of follicle stimulating hormone (FSH), lutropin hormone (LH) and also gonadotropins. Euro-HMG 75IU Injection is injected into the body through the muscle. Using Euro-HMG 75IU Injection may show these side effects; headaches, mood swings, weakness, weight gain, swelling in the area where the injection has been given, enlargement of the breasts and also breast tenderness. The other most common effect of using Euro-HMG 75IU Injection is pain in the abdominal area caused by ovarian hyperstimulation (OHSS). This happens when too many eggs are produced and the ovaries subsequently swell up. The other risk that may arise from taking these shots is that of conceiving twins in case you were not planning for it. Before taking this medication it is advised that you consult and inform your doctor if you have any of the conditions mentioned below: If your are allergic to menotropins or gonadotropins. If you suffer from vaginal bleeding. If you have a ovarian cyst. Dosage differs from person to person. It is generally fixed according to the individual requirement of each patient. Ideally, if you time your conception and try to have intercourse within 12 to 36 hours after Euro-HMG 75IU Injection has been given, chances of you becoming pregnant are higher. In case the first cycle therapy does not work then re-evaluate it. You should have second thoughts about taking Euro-HMG 75IU Injection and consult your doctor if ovulation does not occur even after three cycles of treatment.Sustanon – is one of the most popular steroids today. It highly appreciated by those who use it. The peak of the popularity of this drug has been by ’80 – ’90 years of the twentieth century and at the same time on its popularity a huge number of articles on the pole position of the drug was written. Buy Sustanon – which means to buy one of the most advantageous products of our times. Sustanon has the following advantages: it consists of a mixture of four testosterones, which, thanks to a specific structure have a synergistic effect. All testosterone esters, which are part of Sustanon have different absorption rate and this makes it possible to maintain a constant anabolics level in the blood for a month. Use of injectable Sustanon is enough one time in three weeks. Sustanon Effects and Reviews Sustanon is used to increase the weight. Among the side effects is distinguished gynecomastia, deterioration of natural testosterone by the body, swelling, as well as deposits of fat on the female type. If you decide to buy Sustanon, keep in mind that it can be used only in male persons who have reached twenty-one years How to Use Sustanon: Dosage, Cycle, PCT If you want to achieve the maximum effect from the use of Sustanon, then use it in conjunction with diet and nutrition for a set of muscle mass. This steroid has effects on the body next day and is active for 3-4 weeks. After the cycle, you will notice a strong increase in strength and will gain weight. The course lasts for 6 weeks. It is done a total of 5 or 6 injections. It is necessary to do them once a week (at a dose of 250-500 mg). From the second week of the cycle, it is desirable to start the use of Nolvadex (10 mg daily) and complete its application – 4 weeks after the last injection. Warnings: Keep out of reach of children. For adults only.During any physical work the body produces insulin-like growth factor. It leads to the appearance of a large number of muscle cells causing muscle growth. In addition this substance helps to accelerate the healing process. One of the types of this hormone is a peptide Peg MGF. It is similar to growth hormone because of its characteristics but the main difference is that it does not affect the ligaments and cartilage condition. An active substance MGF has a very short half-life. To increase the effectiveness of the hormone it is possible to create a kind of capsule consisting of polyethylene glycol surrounding the hormone. The human’s body does not react to polyethylene glycol and the transit time of the hormone in the organism can be increased. With this solution Peg MGF peptide has a long lasting effect allowing you to achieve your goals. Peg MGF feedbacks show that this peptide is especially popular among young athletes. It has been proved that the peptide has less effect on elder people so it depends on the age of the athlete. Researches show that the full course allows to increase muscle size by 15%. The effects of Peg MGF It is recommended to buy Peg MGF when you need to: increase the growth of muscle tissue; reduce the number of fat cells in the body; increase endurance and strength; achieve an apparent muscle relief; accelerate the recovery of muscle cells after workout or injury; achieve detailed venous pattern; stimulate the formation of new venous branches. In the addition to the above points, Peg MGF improves immune forces of the body, lowers cholesterol level in blood, strengthens the nervous system, stimulates the formation of bone marrow cells, improves skin and prevents the negative impact of the increased heart stress. Application and dosage of Peg MGF The peptide can be administered in two ways. In first case the dosage for Peg MGF is from 100 to 200 mcg. Preparation can be administered every 2-3 days during 5 or 6 weeks. Then the pause for 3 weeks must be made. It is recommended to inject the peptide immediately after workouts. The course is repeated if necessary until the desired result is achieved. Side effects and contraindications Before beginning a hormone course you must carefully read the instructions for the use of Peg MGF. In rare cases there are possible some complications such as increased growth and size of limbs and prostatic hyperplasia. So peptide administration is allowed under the careful attention of experienced professionals and after consulting a doctor.
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