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Sermorelin is a synthetically made version of growth hormone releasing hormone (GHRH), the endogenous hormone responsible for stimulating natural growth hormone production. Also known as growth hormone releasing factor and GRF 1-29, it is categorized as a growth hormone secretagogue, a compound which stimulates increased secretion of growth hormone from the pituitary gland.
Sermorelin stimulates growth hormone production, thereby increasing muscle mass, decreasing body fat, enhancing recovery, improving sleep, enhancing flexibility and joint health, and improving overall health and wellness.
Sermorelin is used to treat poor growth development (typically in children) due to growth hormone deficiency. It functions by stimulating the pituitary gland to release more natural growth hormone.
Mechanism of Action
Similarly to the body?s natural GHRH, Sermorelin works by attaching to the growth hormone releasing hormone receptor (or GHRHr) in the anterior part of the pituitary gland. There, it works to stimulate the production of growth hormone and begins inducing increases in production of endogenous IGF-1. As it functions in similar manner to GHRH, Sermorelin?s positive effect on growth hormone output is modulated by a negative feedback mechanism initiated by somatostatin, the endogenous hormone also known as growth hormone inhibiting hormone (GHIH). This initiates many positive effects, some of which are the prevention of extreme, unhealthy growth hormone levels in the body and the mirroring of more natural patterns of fluctuation in growth hormone concentrations.
Sermorelin?s natural action mechanism allows for the preservation of the hypothalamic-pituitary-somatotropic axis, preventing the shutdown of hormone production that typically accompanies direct replacement with hGH. Sermorelin has also been shown to improve sleep quality, enhancing the duration of restorative slow wave sleep and amplifying sleep-related secretion of growth hormone while reducing production of cortisol (a catabolic stress hormone).
Mode of Administration: Subcutaneous injection to a fleshy part of the body, typically to the stomach or abdominal area.
Before administering Sermorelin, always be sure to use a clean and sterile syringe.
Hold the Sermorelin vial upright and insert the syringe in the center of the cap.
Draw the plunger until you have the correct amount (see ?Dosage? below) in the syringe and carefully remove it.
Before administering the syringe, use alcohol to cleanse the area of skin.
Pinch the skin around the area to be injected, leave about 2 cm on each side.
Hold the syringe at a 90 degree angle to your skin and swiftly insert the syringe.
Depress the plunger fully, until the syringe is empty, and carefully draw out.
Dosage Amount: 100mcg to 1000mcg (0.10mg to 1.0mg)
Dosage Frequency: 1 - 3 times daily
Sermorelin can either administered once daily before bed or split into 2 ? 3 smaller doses throughout the day. Both approaches to administration can be effective and have been shown to have positive results in clinical studies.
While Sermorelin has a relatively short half-life of up to 20 minutes, it has been shown to stimulate an acute release of growth hormone for two hours after administration. Protocols delivering three daily doses of as little as 100mcg (0.10mg) per administration have been shown to cause a significant increase in growth hormone and IGF-1 secretion.
Sermorelin may generate several mild side effects, including: reaction in the injection site, such as pain, swelling and redness, flushing of the skin, headaches, difficulty swallowing, dizziness or fatigue, hyperactivity, hives, nausea and/or vomiting, change in taste, pallor, and tightness in the chest.
Increase of muscle and lean body mass
Reduction of fat and improved weight loss
Improvement of energy and endurance
Increase of vitality and strength
Acceleration of wound and injury healing
Improvement of cardiovascular and immune function
Enhancement of sleep quality and mood
Improvement of skin quality and higher collagen density||Euro-HMG 75IU Injection or hMG for short is used to treat infertility in women. It is also known by the name of Menotropin. It is a hormonally active drug that stimulates the production of eggs in the ovaries in cases of women who suffer from ovarian failure. Euro-HMG 75IU Injection is extricated from the urine of postmenopausal females. The urine of a postmenopausal woman contains high levels of follicle stimulating hormone (FSH), lutropin hormone (LH) and also gonadotropins. Euro-HMG 75IU Injection is injected into the body through the muscle.
Using Euro-HMG 75IU Injection may show these side effects; headaches, mood swings, weakness, weight gain, swelling in the area where the injection has been given, enlargement of the breasts and also breast tenderness. The other most common effect of using Euro-HMG 75IU Injection is pain in the abdominal area caused by ovarian hyperstimulation (OHSS). This happens when too many eggs are produced and the ovaries subsequently swell up. The other risk that may arise from taking these shots is that of conceiving twins in case you were not planning for it. Before taking this medication it is advised that you consult and inform your doctor if you have any of the conditions mentioned below:
If your are allergic to menotropins or gonadotropins.
If you suffer from vaginal bleeding.
If you have a ovarian cyst.
Dosage differs from person to person. It is generally fixed according to the individual requirement of each patient. Ideally, if you time your conception and try to have intercourse within 12 to 36 hours after Euro-HMG 75IU Injection has been given, chances of you becoming pregnant are higher. In case the first cycle therapy does not work then re-evaluate it. You should have second thoughts about taking Euro-HMG 75IU Injection and consult your doctor if ovulation does not occur even after three cycles of treatment.||CJC-1295 DAC, also known as growth hormone releasing factor (GRF MOD (1-29) or GRF), is an analogue of GHRH (growth hormone releasing hormone).
CJC-1295 is a GHRH (the 44-amino acid long version) with 15 aminos removed, thus a total of 29 amino acids, and bound to DAC it is also called Drug Affinity Complex, and CJC-1295 is often referred to as GHRH with Drug Affinity Complex, this essentially lengthens its life span.
The difference between CJC-1295 and CJC-1295 DAC is that CJC-1295 DAC version CJC-1295 with the addition of so-called. Drug Affinity Complex (DAC), which significantly prolong their effects and action. This means that the product will act in the body much longer than is usual in CJC-1295 (without DAC), namely up to 14 days.
The main effects of CJC-1295 DAC
enhances secretion of growth hormone in the blood;
helps achieve significant muscle hardness;
promotes muscle growth and strength;
helps burn fat effectively;
visibly improves skin quality, has a rejuvenating effect and smooths wrinkles;
increases bone density;
effectively strengthens ligaments and joints;
has a significant positive effect on sleep, regeneration and vitality.
CJC 1295 DAC Stack/Cycle
In order to regenerate the various systems of the body, take CJC-1295 just before going to bed, once per day.
In bodybuilding, for muscle building, a CJC-1295 injection is produced three times a day.
The optimum dose is considered to be 300 mcg per day and it should be divided into three equal parts, to perform injections in the morning, afternoon and evening.
In order to achieve a synergistic effect, in which substantially increases the release of growth hormone, it is practiced co-administration of CJC-1295 and GHRP-2 or GHRP-6.
Duration of CJC-1295 cycle does not have any limitations.
The drug is injected into the body via intramuscular or subcutaneous injection.||TB-500 is a synthetic peptide version of the naturally occuring healing protein present in about all human and mammalian cells known as Thymosin Beta 4 (TB4). Research has shown TB 500 to have beneficial effects on wound healing, injury recovery, flexibility, and inflammation. These desirable effects are accomplished through TB 500’s influence on blood cell and blood vessel development, cellular differentiation, and cell migration. A major part of its healing capability stems from the peptide’s regulation of actin, a cell building protein essential to healing and wound repair.
TB500 comes as a freeze dried (lyophilized) powder. Research has shown that best results are achieved when bacteriostatic sodium chloride 0.9% is used to reconstitute thymosin peptides. TB 500 dosages can range from 5mg to 20 mg per week. Administration is generally divided into 2-3 injections per week. Once the peptide is built up in the system, the weekly dosage is generally lowered a bit to a maintenance dosage of about half or less of the original weekly dose. Administration of maintenance dosage can be made once per week.
TB500 is typically injected subcutaneously, though it can also be injected into muscle if desired.
How to Store TB 500: Store the product at room temperature in a non-humid environment. The vial should be shielded from light. An opened vial can be kept for up to 8 days refrigerated.
What is TB-500
TB 500 research illustrates multiple properties that have provided the impetus for a worldwide series of clinical trials of potential effectiveness for thymosin beta-4 in promoting repair of wounds in skin, cornea and heart. Thymosin beta 4 is produced in the thymus gland and is found in high concentrations in wound fluids. As such it has been observed to facilitate healing of injured tissue in the body.
TB-500 is a naturally occurring peptide found in high concentrations in blood platelets, wound fluid and other tissues. TB-500 peptides for research are not growth factors; rather major actin regulating protein peptides. TB 500 has been found to play an important role in protection, regeneration and remodeling of injured and/or damaged tissues. The gene for Thymosin Beta-4 has also been found to be one of the first to be stimulated after an incident of injury.
Present in almost all human and animal cells, Thymosin Beta 4 is naturally occurring wound healing peptide. TB 500 is a synthetically made version of TB4 that facilitates healing and recovery by helping build new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration. For the overworked or injured individual, TB 500 offers extremely enticing wound healing effects.
How Does TB 500 Work?
TB 500 is able to help recovery by exerting effects on actin. By up-regulating this cellular protein, TB 500 is able to capitalize on actin’s positive effects. These include the promotion of cell migration and proliferation. As a result, new blood vessels form and inflammation can be regulated so that healing and recovery are optimized. In addition, TB 500’s unique molecular structure allows it to travel long distances in the body. This enables it to exert a “systemic” effect, seeking out and helping those areas of the body suffering injury. Further beneficial results of TB 500 administration can include reduced inflammation and enhanced flexibility. There have even been some reports of regrowing and darkening of hair.
What TB 500 Side Effects Are There?
There are many positive effects associated with Tb500 use, including enhanced recovery, reduced inflammation, and improved flexibility. The peptide works very effectively to aid recovery of slow healing injuries such as those to connective tissue, i.e. tendons and ligaments. Muscle injuries and injuries to skin are greatly helped as well. From reports from users and researchers around the globe, TB 500 seems to cause very few, if any, serious negative side effects.
Most peptides generally can produce a lightheadedness or nauseous feeling upon injection. Also, flu-like symptoms are prevalent among many other peptides as well. However, the incidence of these negative side effects occurring with TB500 administration is reported to be very low, if at all. TB 500 appears to be a very well tolerated peptide among users.
The information presented on this web site is not intended to take the place of your personal physician’s advice and is not intended to diagnose, treat, cure or prevent any disease.||MGF is an acronym for Mechano Growth Factor. This may be a chemical that many users of conventional drugs do not recognise. This is because it is a replica of a very specific molecular signal and an offshoot of the Insulin-like Growth Factor 1 (IGF-1).
As such, this item is usually only used by more seasoned practitioners looking to boost recovery and subsequent gains in muscle strength, power and mass.
This is because Mechano Growth Factor is a molecular signal used in the body to signal surrounding cells, known as “satellite cells”, to migrate into the muscle and become part of the muscle cell.
This creates a bigger muscle cell and can permanently increase the potential size and force capacity of a given muscle fibre. Therefore it may help improve an athlete’s potential even after a user has stopped including it in their regimen.
So, it is no wonder why many individuals, like aesthetic competitors or sportspeople, seek out the Mechano Growth Factor 2 mg peptide.
However, because of its relative lack of therapeutic uses, compared to other items for those with medical ailments or those who don’t utilise it for the above reasons, it is incredibly difficult to find this item from conventional vendors such as pharmacies or medical facilities.
This means that, if you are looking for these types of agents, you’ll have to buy peptides online, much like many other similar chemicals which are used for related purposes.
However, before getting this, or any other similar item, it is key to understand how this item may be included in a regime in order to get the desired outcomes for which it is acquired. So, below, we look at how this agent is commonly included in regimens, how much of it is used, as well as when, and potential drawbacks to its inclusion in your programme.
Mechano Growth Factor Peptide Doses and Timing
There is a relative scarcity of research looking at what MGF peptide dosage is most ideal for those using it purely to boost size or athletic capability.
However, larger amounts have been reported to produce better outcomes than smaller ones. In terms of a commonly reported amount, the MGF 2mg thrice weekly over a period of four weeks has been used by many of those looking for athletic or structural benefit.
In terms of timing these MGF doses, this agent is usually administered immediately after a workout. The reason for this is due to the relatively short half-life of the chemical, which has a half-life lasting only a few minutes. This means it will be broken down and processed by the body only a few minutes after it has been administered.
So, users choose to administer it directly after a workout where the body is in the process of renewal and repair and anabolic signalling will be strong. But, if administering this item immediately after a workout is not a viable option for some, then the best alternative would be to instead include an esterified form of the agent such as MGF-PEG, which has a polyethylene glycol attachment to extend its half-life to several days.
This can afford a more gradual release and processing of the agent in the body and allows a lot more freedom of when the Mechano Growth Factor can be administered.
The above information should help you select the form of the chemical best suited to your needs and lifestyle, as well as how best to use your form in an attempt to maximize your results from the agent. Now, we can look at the potential adverse events associated with the use of this agent that should be considered when looking at getting it for your regimen.
MGF Peptide Side Effects
Much like the perks behind the use of this agent, research looking at the adverse events associated with the use of this growth factor, or other related new items such as fragment 176-191, particularly for the purposes listed in the above sections, is very thin.
This makes it hard to outline the range of drawbacks that may impact the vast majority of users.
However, from reviewing reports from previous users and suppliers, some MGF peptide side effects can include:
Pain or irritation surrounding the site of administration, as is common with a lot of injectable solutions;
Potential cardiac issues or irregularities.
These should all be considered before you buy MGF peptide to ensure you are on the lookout for any particular issues with use and ensure an enjoyable, effective and efficient period of use.|